IL17B (interleukin 17B)

2014-08-01  

Identity

HGNC
LOCATION
5q32
LOCUSID
ALIAS
IL-17B,IL-20,NIRF,ZCYTO7

Other Information

Locus ID:

NCBI: 27190
MIM: 604627
HGNC: 5982
Ensembl: ENSG00000127743

Variants:

dbSNP: 27190
ClinVar: 27190
TCGA: ENSG00000127743
COSMIC: IL17B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127743ENST00000261796Q9UHF5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Cytokine-cytokine receptor interactionKEGGhsa04060
IL-17 signaling pathwayKEGGko04657
IL-17 signaling pathwayKEGGhsa04657

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380331682023Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda.0
380331682023Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda.0
355704062022Potential role of INTERLEUKIN-17 in the pathogenesis of oral lichen planus: a systematic review with META-analysis.6
355704062022Potential role of INTERLEUKIN-17 in the pathogenesis of oral lichen planus: a systematic review with META-analysis.6
307704172019Cutting Edge: IL-17B Uses IL-17RA and IL-17RB to Induce Type 2 Inflammation from Human Lymphocytes.18
307704172019Cutting Edge: IL-17B Uses IL-17RA and IL-17RB to Induce Type 2 Inflammation from Human Lymphocytes.18
294965382018A positive feedback loop of IL-17B-IL-17RB activates ERK/β-catenin to promote lung cancer metastasis.19
294965382018A positive feedback loop of IL-17B-IL-17RB activates ERK/β-catenin to promote lung cancer metastasis.19
277031472017Variants in SKP1, PROB1, and IL17B genes at keratoconus 5q31.1-q35.3 susceptibility locus identified by whole-exome sequencing.9
281458812017IL-17B activated mesenchymal stem cells enhance proliferation and migration of gastric cancer cells.14
281607542017The role of IL17B-IL17RB signaling pathway in breast cancer.29
277031472017Variants in SKP1, PROB1, and IL17B genes at keratoconus 5q31.1-q35.3 susceptibility locus identified by whole-exome sequencing.9
281458812017IL-17B activated mesenchymal stem cells enhance proliferation and migration of gastric cancer cells.14
281607542017The role of IL17B-IL17RB signaling pathway in breast cancer.29
271468812016Non-tumor tissue derived interleukin-17B activates IL-17RB/AKT/β-catenin pathway to enhance the stemness of gastric cancer.22

Citation

Dessen P

IL17B (interleukin 17B)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54833/haematological-explorer/js/lib/bootstrap.min.js