CLPS (colipase)

2014-09-01 Affiliation

Identity

HGNC

CLPS

LOCATION

6p21.31

LOCUSID

1208

ALIAS

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 1208
MIM: 120105
HGNC: 2085
Ensembl: ENSG00000137392

Variants:

dbSNP: 1208
ClinVar: 1208
TCGA: ENSG00000137392
COSMIC: CLPS

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000137392	ENST00000259938	P04118
ENSG00000137392	ENST00000616014	A0A087X0Q7
ENSG00000137392	ENST00000622413	A0A087WZW1

Expression (GTEx)

5000

10000

15000

20000

25000

30000

35000

40000

45000

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Fat digestion and absorption	KEGG	ko04975
Fat digestion and absorption	KEGG	hsa04975
Signal Transduction	REACTOME	R-HSA-162582
Visual phototransduction	REACTOME	R-HSA-2187338
Retinoid metabolism and transport	REACTOME	R-HSA-975634
Metabolism	REACTOME	R-HSA-1430728
Metabolism of lipids and lipoproteins	REACTOME	R-HSA-556833
Lipid digestion, mobilization, and transport	REACTOME	R-HSA-73923
Digestion of dietary lipid	REACTOME	R-HSA-192456
Metabolism of vitamins and cofactors	REACTOME	R-HSA-196854
Metabolism of fat-soluble vitamins	REACTOME	R-HSA-6806667

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
23204298	2013	The Arg92Cys colipase polymorphism impairs function and secretion by increasing protein misfolding.	2
23918603	2013	Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer.	159
23204298	2013	The Arg92Cys colipase polymorphism impairs function and secretion by increasing protein misfolding.	2
23918603	2013	Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer.	159
18726866	2009	Genetic variability of procolipase associates with altered insulin secretion in non-diabetic Caucasians.	7
18726866	2009	Genetic variability of procolipase associates with altered insulin secretion in non-diabetic Caucasians.	7
20054203	2009	Procolipase gene: no association with early-onset obesity or fat intake.	2
20054203	2009	Procolipase gene: no association with early-onset obesity or fat intake.	2
18726866	2009	Genetic variability of procolipase associates with altered insulin secretion in non-diabetic Caucasians.	7
18726866	2009	Genetic variability of procolipase associates with altered insulin secretion in non-diabetic Caucasians.	7
20054203	2009	Procolipase gene: no association with early-onset obesity or fat intake.	2
20054203	2009	Procolipase gene: no association with early-onset obesity or fat intake.	2
17715423	2007	A polymorphism in the gene encoding procolipase produces a colipase, Arg92Cys, with decreased function against long-chain triglycerides.	4
17715423	2007	A polymorphism in the gene encoding procolipase produces a colipase, Arg92Cys, with decreased function against long-chain triglycerides.	4
16189801	2005	Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations.	7

Citation

Dessen P

CLPS (colipase)

Atlas Genet Cytogenet Oncol Haematol. 2014-09-01

Online version: http://atlasgeneticsoncology.org/gene/54878