STMN2 (stathmin 2)

2014-09-01  

Identity

HGNC
STMN2
LOCATION
8q21.13
LOCUSID
11075
ALIAS
SCG10,SCGN10
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 11075
MIM: 600621
HGNC: 10577
Ensembl: ENSG00000104435

Variants:

dbSNP: 11075
ClinVar: 11075
TCGA: ENSG00000104435
COSMIC: STMN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104435ENST00000220876Q93045
ENSG00000104435ENST00000518111Q93045
ENSG00000104435ENST00000518491E5RGX5

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900
1000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
381753012024Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer's disease.5
381753012024Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer's disease.5
358760652023Analysis of STMN2 CA repeats in italian ALS patients shows no association.0
364608042023STMN2 overexpression promotes cell proliferation and EMT in pancreatic cancer mediated by WNT/β-catenin signaling.2
370123642023TDP43 blocks misprocessing of STMN2 RNA.0
358760652023Analysis of STMN2 CA repeats in italian ALS patients shows no association.0
364608042023STMN2 overexpression promotes cell proliferation and EMT in pancreatic cancer mediated by WNT/β-catenin signaling.2
370123642023TDP43 blocks misprocessing of STMN2 RNA.0
356135202022NEK1 and STMN2 short tandem repeat lengths are not associated with Australian amyotrophic lateral sclerosis risk.0
356135202022NEK1 and STMN2 short tandem repeat lengths are not associated with Australian amyotrophic lateral sclerosis risk.0
337058632021STMN2 mediates nuclear translocation of Smad2/3 and enhances TGFβ signaling by destabilizing microtubules to promote epithelial-mesenchymal transition in hepatocellular carcinoma.8
337058632021STMN2 mediates nuclear translocation of Smad2/3 and enhances TGFβ signaling by destabilizing microtubules to promote epithelial-mesenchymal transition in hepatocellular carcinoma.8
327906442020Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia.86
327906442020Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia.86
306432922019ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair.246

Citation

Dessen P

STMN2 (stathmin 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-09-01

Online version: http://atlasgeneticsoncology.org/gene/54882