SCX (scleraxis bHLH transcription factor)

2014-09-01  

Identity

HGNC
SCX
LOCATION
8q24.3
LOCUSID
642658
ALIAS
SCXA,SCXB,bHLHa48

Other Information

Locus ID:

NCBI: 642658
MIM: 609067
HGNC: 32322
Ensembl: ENSG00000260428

Variants:

dbSNP: 642658
ClinVar: 642658
TCGA: ENSG00000260428
COSMIC: SCX

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000260428ENST00000567180Q7RTU7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
355637782022Regulation of Cardiac Fibroblast GLS1 Expression by Scleraxis.2
355637782022Regulation of Cardiac Fibroblast GLS1 Expression by Scleraxis.2
320275172020Scleraxis as a prognostic marker of myocardial fibrosis in hypertrophic cardiomyopathy (SPARC) study.1
321830512020Tenogenic Contribution to Skeletal Muscle Regeneration: The Secretome of Scleraxis Overexpressing Mesenchymal Stem Cells Enhances Myogenic Differentiation In Vitro.4
327085892020The Transcription Factor SCX is a Potential Serum Biomarker of Fibrotic Diseases.5
327955902020The transcription factor scleraxis differentially regulates gene expression in tenocytes isolated at different developmental stages.3
320275172020Scleraxis as a prognostic marker of myocardial fibrosis in hypertrophic cardiomyopathy (SPARC) study.1
321830512020Tenogenic Contribution to Skeletal Muscle Regeneration: The Secretome of Scleraxis Overexpressing Mesenchymal Stem Cells Enhances Myogenic Differentiation In Vitro.4
327085892020The Transcription Factor SCX is a Potential Serum Biomarker of Fibrotic Diseases.5
327955902020The transcription factor scleraxis differentially regulates gene expression in tenocytes isolated at different developmental stages.3
297509942018Regulation of cardiac fibroblast MMP2 gene expression by scleraxis.10
299062252018Scleraxis regulates Twist1 and Snai1 expression in the epithelial-to-mesenchymal transition.20
297509942018Regulation of cardiac fibroblast MMP2 gene expression by scleraxis.10
299062252018Scleraxis regulates Twist1 and Snai1 expression in the epithelial-to-mesenchymal transition.20
268510782016Pharmacological Regulation of In Situ Tissue Stem Cells Differentiation for Soft Tissue Calcification Treatment.16

Citation

Dessen P

SCX (scleraxis bHLH transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-09-01

Online version: http://atlasgeneticsoncology.org/gene/54888