GPD1L (glycerol-3-phosphate dehydrogenase 1 like)

2014-10-01  

Identity

HGNC
GPD1L
LOCATION
3p22.3
LOCUSID
23171
ALIAS
GPD1-L
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23171
MIM: 611778
HGNC: 28956
Ensembl: ENSG00000152642

Variants:

dbSNP: 23171
ClinVar: 23171
TCGA: ENSG00000152642
COSMIC: GPD1L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000152642ENST00000282541Q8N335
ENSG00000152642ENST00000425459C9JM46
ENSG00000152642ENST00000428684F8WC16
ENSG00000152642ENST00000429432C9K0P5
ENSG00000152642ENST00000431009C9JFA7

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Glycerophospholipid metabolismKEGGko00564
Glycerophospholipid metabolismKEGGhsa00564
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Triglyceride BiosynthesisREACTOMER-HSA-75109
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Synthesis of PAREACTOMER-HSA-1483166

References

Pubmed IDYearTitleCitations
373829622023GPD1L inhibits renal cell carcinoma progression by regulating PINK1/Parkin-mediated mitophagy.4
376859192023Prognostic and Predictive Utility of GPD1L in Human Hepatocellular Carcinoma.0
373829622023GPD1L inhibits renal cell carcinoma progression by regulating PINK1/Parkin-mediated mitophagy.4
376859192023Prognostic and Predictive Utility of GPD1L in Human Hepatocellular Carcinoma.0
360645582022Atrial myocyte-derived exosomal microRNA contributes to atrial fibrosis in atrial fibrillation.10
360645582022Atrial myocyte-derived exosomal microRNA contributes to atrial fibrosis in atrial fibrillation.10
331071742021GPD1L is negatively associated with HIF1α expression and predicts lymph node metastasis in oral and HPV- Oropharyngeal cancer.6
331071742021GPD1L is negatively associated with HIF1α expression and predicts lymph node metastasis in oral and HPV- Oropharyngeal cancer.6
319222482020A novel mutation in GPD1‑L associated with early repolarization syndrome via modulation of cardiomyocyte fast sodium currents.3
319222482020A novel mutation in GPD1‑L associated with early repolarization syndrome via modulation of cardiomyocyte fast sodium currents.3
316582442019Long Noncoding RNA Nuclear Enriched Abundant Transcript 1 (NEAT1) Regulates Proliferation, Apoptosis, and Inflammation of Chondrocytes via the miR-181a/Glycerol-3-Phosphate Dehydrogenase 1-Like (GPD1L) Axis.15
316582442019Long Noncoding RNA Nuclear Enriched Abundant Transcript 1 (NEAT1) Regulates Proliferation, Apoptosis, and Inflammation of Chondrocytes via the miR-181a/Glycerol-3-Phosphate Dehydrogenase 1-Like (GPD1L) Axis.15
290772582018Whole-exome sequencing identifies a novel mutation of GPD1L (R189X) associated with familial conduction disease and sudden death.6
290772582018Whole-exome sequencing identifies a novel mutation of GPD1L (R189X) associated with familial conduction disease and sudden death.6
282802582017miR-181a Modulates Chondrocyte Apoptosis by Targeting Glycerol-3-Phosphate Dehydrogenase 1-Like Protein (GPD1L) in Osteoarthritis.16

Citation

Dessen P

GPD1L (glycerol-3-phosphate dehydrogenase 1 like)

Atlas Genet Cytogenet Oncol Haematol. 2014-10-01

Online version: http://atlasgeneticsoncology.org/gene/54913/case-report-explorer/cancer-prone-explorer/favicon/favicon-16x16.png