BMP8A (bone morphogenetic protein 8a)

2015-02-01  

Identity

HGNC
BMP8A
LOCATION
1p34.3
LOCUSID
353500
ALIAS
OP-2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 353500
HGNC: 21650
Ensembl: ENSG00000183682

Variants:

dbSNP: 353500
ClinVar: 353500
TCGA: ENSG00000183682
COSMIC: BMP8A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183682ENST00000331593Q7Z5Y6

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
TGF-beta signaling pathwayKEGGko04350
TGF-beta signaling pathwayKEGGhsa04350
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
BMP signalingKEGGhsa_M00679
BMP signalingKEGGM00679

References

Pubmed IDYearTitleCitations
365941562023Recent progress in the biology and physiology of BMP-8a.1
365941562023Recent progress in the biology and physiology of BMP-8a.1
333385492021Human bone morphogenetic protein 8A promotes expansion and prevents apoptosis of cumulus cells in vitro.7
333385492021Human bone morphogenetic protein 8A promotes expansion and prevents apoptosis of cumulus cells in vitro.7
316561612020Serous BMP8A has Clinical Significance in the Ultrasonic Diagnosis of Thyroid Cancer and Promotes Thyroid Cancer Cell Progression.4
319402752020Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway.4
321289172020BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.18
316561612020Serous BMP8A has Clinical Significance in the Ultrasonic Diagnosis of Thyroid Cancer and Promotes Thyroid Cancer Cell Progression.4
319402752020Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway.4
321289172020BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.18
284654132017BMP8A sustains spermatogenesis by activating both SMAD1/5/8 and SMAD2/3 in spermatogonia.19
284654132017BMP8A sustains spermatogenesis by activating both SMAD1/5/8 and SMAD2/3 in spermatogonia.19
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
204244732010L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.0
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37

Citation

Dessen P

BMP8A (bone morphogenetic protein 8a)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/54986