MRGPRD (MAS related GPR family member D)

2015-02-01  

Identity

HGNC
MRGPRD
LOCATION
11q13.3
LOCUSID
116512
ALIAS
MRGD,TGR7

Other Information

Locus ID:

NCBI: 116512
MIM: 607231
HGNC: 29626
Ensembl: ENSG00000172938

Variants:

dbSNP: 116512
ClinVar: 116512
TCGA: ENSG00000172938
COSMIC: MRGPRD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172938ENST00000309106Q8TDS7

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Renin-angiotensin systemKEGGko04614
Renin-angiotensin systemKEGGhsa04614

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
383387782024The Expression of Alamandine Receptor MrgD in Clear Cell Renal Cell Carcinoma Is Associated with a Worse Prognosis and Unfavorable Response to Antiangiogenic Therapy.0
383387782024The Expression of Alamandine Receptor MrgD in Clear Cell Renal Cell Carcinoma Is Associated with a Worse Prognosis and Unfavorable Response to Antiangiogenic Therapy.0
338915442021Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates.19
349480512021Constitutive, Basal, and β-Alanine-Mediated Activation of the Human Mas-Related G Protein-Coupled Receptor D Induces Release of the Inflammatory Cytokine IL-6 and Is Dependent on NF-κB Signaling.6
338915442021Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates.19
349480512021Constitutive, Basal, and β-Alanine-Mediated Activation of the Human Mas-Related G Protein-Coupled Receptor D Induces Release of the Inflammatory Cytokine IL-6 and Is Dependent on NF-κB Signaling.6
234467382013Discovery and characterization of alamandine: a novel component of the renin-angiotensin system.119
234467382013Discovery and characterization of alamandine: a novel component of the renin-angiotensin system.119
227153972012MRGD, a MAS-related G-protein coupled receptor, promotes tumorigenisis and is highly expressed in lung cancer.12
227153972012MRGD, a MAS-related G-protein coupled receptor, promotes tumorigenisis and is highly expressed in lung cancer.12
186363142008Angiotensin metabolites can stimulate receptors of the Mas-related genes family.36
186363142008Angiotensin metabolites can stimulate receptors of the Mas-related genes family.36

Citation

Dessen P

MRGPRD (MAS related GPR family member D)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/55074