RNU6-1 (RNA, U6 small nuclear 1)

2015-04-01  

Identity

HGNC
RNU6-1
LOCATION
10p13
LOCUSID
26827
ALIAS
RNU6,RNU6A,U6,U6-1

Other Information

Locus ID:

NCBI: 26827
MIM: 180692
HGNC: 10227
Ensembl: ENSG00000206625

Variants:

dbSNP: 26827
ClinVar: 26827
TCGA: ENSG00000206625
COSMIC: RNU6-1

RNA/Proteins

Expression (GTEx)

0
1
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
RNA transportKEGGko03013
RNA transportKEGGhsa03013

References

Pubmed IDYearTitleCitations
381650502024THUMPD2 catalyzes the N2-methylation of U6 snRNA of the spliceosome catalytic center and regulates pre-mRNA splicing and retinal degeneration.0
384269352024Splicing analysis of STAT3 tandem donor suggests non-canonical binding registers for U1 and U6 snRNAs.0
381650502024THUMPD2 catalyzes the N2-methylation of U6 snRNA of the spliceosome catalytic center and regulates pre-mRNA splicing and retinal degeneration.0
384269352024Splicing analysis of STAT3 tandem donor suggests non-canonical binding registers for U1 and U6 snRNAs.0
372830532023N 2-methylguanosine modifications on human tRNAs and snRNA U6 are important for cell proliferation, protein translation and pre-mRNA splicing.6
372830532023N 2-methylguanosine modifications on human tRNAs and snRNA U6 are important for cell proliferation, protein translation and pre-mRNA splicing.6
349937252022Small non-coding RNA profiling in breast cancer: plasma U6 snRNA, miR-451a and miR-548b-5p as novel diagnostic and prognostic biomarkers.8
349937252022Small non-coding RNA profiling in breast cancer: plasma U6 snRNA, miR-451a and miR-548b-5p as novel diagnostic and prognostic biomarkers.8
246067282014Identification of suitable reference genes for hepatic microRNA quantitation.31
246067282014Identification of suitable reference genes for hepatic microRNA quantitation.31
234268752013Conformational heterogeneity of the protein-free human spliceosomal U2-U6 snRNA complex.4
243494252013Identification and validation of reference genes for qPCR detection of serum microRNAs in colorectal adenocarcinoma patients.59
234268752013Conformational heterogeneity of the protein-free human spliceosomal U2-U6 snRNA complex.4
243494252013Identification and validation of reference genes for qPCR detection of serum microRNAs in colorectal adenocarcinoma patients.59

Citation

Dessen P

RNU6-1 (RNA, U6 small nuclear 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-04-01

Online version: http://atlasgeneticsoncology.org/gene/55173