MAP7D3 (MAP7 domain containing 3)

2015-05-01  

Identity

HGNC
MAP7D3
LOCATION
Xq26.3
LOCUSID
79649
ALIAS
MDP3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79649
MIM: 300930
HGNC: 25742
Ensembl: ENSG00000129680

Variants:

dbSNP: 79649
ClinVar: 79649
TCGA: ENSG00000129680
COSMIC: MAP7D3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129680ENST00000316077Q8IWC1
ENSG00000129680ENST00000370660A0A0A0MRP0
ENSG00000129680ENST00000370661Q8IWC1
ENSG00000129680ENST00000370663Q8IWC1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
307704342019MAP7 family proteins regulate kinesin-1 recruitment and activation.66
307704342019MAP7 family proteins regulate kinesin-1 recruitment and activation.66
272840042016DDA3 and Mdp3 modulate Kif2a recruitment onto the mitotic spindle to control minus-end spindle dynamics.9
272840042016DDA3 and Mdp3 modulate Kif2a recruitment onto the mitotic spindle to control minus-end spindle dynamics.9
246145952014Microtubule stabilization by Mdp3 is partially attributed to its modulation of HDAC6 in addition to its association with tubulin and microtubules.10
249275012014C-terminal region of MAP7 domain containing protein 3 (MAP7D3) promotes microtubule polymerization by binding at the C-terminal tail of tubulin.13
251617032014Microtubule-associated protein Mdp3 promotes breast cancer growth and metastasis.16
246145952014Microtubule stabilization by Mdp3 is partially attributed to its modulation of HDAC6 in addition to its association with tubulin and microtubules.10
249275012014C-terminal region of MAP7 domain containing protein 3 (MAP7D3) promotes microtubule polymerization by binding at the C-terminal tail of tubulin.13
251617032014Microtubule-associated protein Mdp3 promotes breast cancer growth and metastasis.16
221429022011Mdp3 is a novel microtubule-binding protein that regulates microtubule assembly and stability.21
221429022011Mdp3 is a novel microtubule-binding protein that regulates microtubule assembly and stability.21

Citation

Dessen P

MAP7D3 (MAP7 domain containing 3)

Atlas Genet Cytogenet Oncol Haematol. 2015-05-01

Online version: http://atlasgeneticsoncology.org/gene/55197/favicon/manifest.json