DUSP28 (dual specificity phosphatase 28)

2015-08-01  

Identity

HGNC
DUSP28
LOCATION
2q37.3
LOCUSID
285193
ALIAS
DUSP26,VHP

Other Information

Locus ID:

NCBI: 285193
HGNC: 33237
Ensembl: ENSG00000188542

Variants:

dbSNP: 285193
ClinVar: 285193
TCGA: ENSG00000188542
COSMIC: DUSP28

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000188542ENST00000343217Q4G0W2
ENSG00000188542ENST00000405954Q4G0W2
ENSG00000188542ENST00000438823H7C234

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
365200872022DUSP28 promotes cell proliferation, migration, and invasion by Akt/β-catenin/Slug axis in breast cancer.0
365200872022DUSP28 promotes cell proliferation, migration, and invasion by Akt/β-catenin/Slug axis in breast cancer.0
309025622019Scattered DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine and paracrine signaling in metastatic pancreatic cancer.0
309025622019Scattered DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine and paracrine signaling in metastatic pancreatic cancer.0
289865882017Autocrine DUSP28 signaling mediates pancreatic cancer malignancy via regulation of PDGF-A.12
291210832017Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28.3
289865882017Autocrine DUSP28 signaling mediates pancreatic cancer malignancy via regulation of PDGF-A.12
291210832017Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28.3
272306792016DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.12
272306792016DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.12
262126642015Blockade of dual-specificity phosphatase 28 decreases chemo-resistance and migration in human pancreatic cancer cells.9
262126642015Blockade of dual-specificity phosphatase 28 decreases chemo-resistance and migration in human pancreatic cancer cells.9
252307052014DUSP28 contributes to human hepatocellular carcinoma via regulation of the p38 MAPK signaling.12
252307052014DUSP28 contributes to human hepatocellular carcinoma via regulation of the p38 MAPK signaling.12

Citation

Dessen P

DUSP28 (dual specificity phosphatase 28)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55311/img/js/lib/meetings/css/template-nav.css