MICALL2 (MICAL like 2)

2015-08-01  

Identity

HGNC
MICALL2
LOCATION
7p22.3
LOCUSID
79778
ALIAS
JRAB,MICAL-L2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79778
HGNC: 29672
Ensembl: ENSG00000164877

Variants:

dbSNP: 79778
ClinVar: 79778
TCGA: ENSG00000164877
COSMIC: MICALL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164877ENST00000297508Q8IY33
ENSG00000164877ENST00000413446Q8IY33

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Tight junctionKEGGko04530
Tight junctionKEGGhsa04530

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382036922023Comprehensive Analysis of MICALL2 Reveals Its Potential Roles in EGFR Stabilization and Ovarian Cancer Cell Invasion.0
382036922023Comprehensive Analysis of MICALL2 Reveals Its Potential Roles in EGFR Stabilization and Ovarian Cancer Cell Invasion.0
363078412022MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.4
363078412022MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.4
339763492021JRAB/MICAL-L2 undergoes liquid-liquid phase separation to form tubular recycling endosomes.2
339763492021JRAB/MICAL-L2 undergoes liquid-liquid phase separation to form tubular recycling endosomes.2
310341582019MICAL-L2 potentiates Cdc42-dependent EGFR stability and promotes gastric cancer cell migration.17
310341582019MICAL-L2 potentiates Cdc42-dependent EGFR stability and promotes gastric cancer cell migration.17
284168122018A new locus regulating MICALL2 expression was identified for association with executive inhibition in children with attention deficit hyperactivity disorder.9
284168122018A new locus regulating MICALL2 expression was identified for association with executive inhibition in children with attention deficit hyperactivity disorder.9
258645912015Silencing of MICAL-L2 suppresses malignancy of ovarian cancer by inducing mesenchymal-epithelial transition.23
258645912015Silencing of MICAL-L2 suppresses malignancy of ovarian cancer by inducing mesenchymal-epithelial transition.23
178911732008Involvement of Rab13 and JRAB/MICAL-L2 in epithelial cell scattering.19
178911732008Involvement of Rab13 and JRAB/MICAL-L2 in epithelial cell scattering.19

Citation

Dessen P

MICALL2 (MICAL like 2)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55340