MKX (mohawk homeobox)

2015-10-01 Affiliation

Identity

HGNC

MKX

LOCATION

10p12.1

LOCUSID

283078

ALIAS

C10orf48,IFRX,IRXL1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 283078
MIM: 601332
HGNC: 23729
Ensembl: ENSG00000150051

Variants:

dbSNP: 283078
ClinVar: 283078
TCGA: ENSG00000150051
COSMIC: MKX

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000150051	ENST00000375790	Q8IYA7
ENSG00000150051	ENST00000419761	Q8IYA7
ENSG00000150051	ENST00000460919	H0YKC7
ENSG00000150051	ENST00000561227	H0YMU2

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
36834493	2023	COBL, MKX and MYOC Are Potential Regulators of Brown Adipose Tissue Development Associated with Obesity-Related Metabolic Dysfunction in Children.	1
36834493	2023	COBL, MKX and MYOC Are Potential Regulators of Brown Adipose Tissue Development Associated with Obesity-Related Metabolic Dysfunction in Children.	1
33115953	2020	Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity.	17
33115953	2020	Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity.	17
27527664	2016	Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.	58
27527664	2016	Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.	58
25312837	2015	Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo.	55
25332192	2015	Mohawk promotes the tenogenesis of mesenchymal stem cells through activation of the TGFβ signaling pathway.	85
25312837	2015	Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo.	55
25332192	2015	Mohawk promotes the tenogenesis of mesenchymal stem cells through activation of the TGFβ signaling pathway.	85
23686683	2013	Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation.	19
23686683	2013	Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation.	19
20634891	2010	Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.	28
20634891	2010	Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.	28
16077953	2005	In silico characterization of an Iroquois family-related homeodomain protein.	0

Citation

Dessen P

MKX (mohawk homeobox)

Atlas Genet Cytogenet Oncol Haematol. 2015-10-01

Online version: http://atlasgeneticsoncology.org/gene/55418