CLIP3 (CAP-Gly domain containing linker protein 3)

2015-10-01  

Identity

HGNC
LOCATION
19q13.12
LOCUSID
ALIAS
CLIPR-59,CLIPR59,RSNL1

Other Information

Locus ID:

NCBI: 25999
MIM: 607382
HGNC: 24314
Ensembl: ENSG00000105270

Variants:

dbSNP: 25999
ClinVar: 25999
TCGA: ENSG00000105270
COSMIC: CLIP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105270ENST00000360535Q96DZ5
ENSG00000105270ENST00000590559K7ESF3
ENSG00000105270ENST00000592017K7ESF3
ENSG00000105270ENST00000593074Q96DZ5

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Death Receptor SignallingREACTOMER-HSA-73887
TNF signalingREACTOMER-HSA-75893
Regulation of TNFR1 signalingREACTOMER-HSA-5357905

References

Pubmed IDYearTitleCitations
344888212021Downregulated CLIP3 induces radioresistance by enhancing stemness and glycolytic flux in glioblastoma.15
344888212021Downregulated CLIP3 induces radioresistance by enhancing stemness and glycolytic flux in glioblastoma.15
276138192016MicroRNA-593-3p regulates insulin-promoted glucose consumption by targeting Slc38a1 and CLIP3.4
276138192016MicroRNA-593-3p regulates insulin-promoted glucose consumption by targeting Slc38a1 and CLIP3.4
260176712015Spy1 induces de-ubiquitinating of RIP1 arrest and confers glioblastoma's resistance to tumor necrosis factor (TNF-α)-induced apoptosis through suppressing the association of CLIPR-59 and CYLD.6
260176712015Spy1 induces de-ubiquitinating of RIP1 arrest and confers glioblastoma's resistance to tumor necrosis factor (TNF-α)-induced apoptosis through suppressing the association of CLIPR-59 and CYLD.6
240017712013DHHC17 palmitoylates ClipR-59 and modulates ClipR-59 association with the plasma membrane.20
240017712013DHHC17 palmitoylates ClipR-59 and modulates ClipR-59 association with the plasma membrane.20
222972962012CLIPR-59 regulates TNF-α-induced apoptosis by controlling ubiquitination of RIP1.15
222972962012CLIPR-59 regulates TNF-α-induced apoptosis by controlling ubiquitination of RIP1.15
200522882010Role of GD3-CLIPR-59 association in lymphoblastoid T cell apoptosis triggered by CD95/Fas.15
200522882010Role of GD3-CLIPR-59 association in lymphoblastoid T cell apoptosis triggered by CD95/Fas.15
152629902004CLIPR-59 is a lipid raft-associated protein containing a cytoskeleton-associated protein glycine-rich domain (CAP-Gly) that perturbs microtubule dynamics.15
152629902004CLIPR-59 is a lipid raft-associated protein containing a cytoskeleton-associated protein glycine-rich domain (CAP-Gly) that perturbs microtubule dynamics.15
118543072002CLIPR-59, a new trans-Golgi/TGN cytoplasmic linker protein belonging to the CLIP-170 family.19

Citation

Dessen P

CLIP3 (CAP-Gly domain containing linker protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2015-10-01

Online version: http://atlasgeneticsoncology.org/gene/55458/gene-fusions-explorer/js/tumors-explorer/