EPN2 (epsin 2)

2016-01-01  

Identity

HGNC
EPN2
LOCATION
17p11.2
LOCUSID
22905
ALIAS
EHB21
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 22905
MIM: 607263
HGNC: 18639
Ensembl: ENSG00000072134

Variants:

dbSNP: 22905
ClinVar: 22905
TCGA: ENSG00000072134
COSMIC: EPN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000072134ENST00000314728O95208
ENSG00000072134ENST00000347697O95208
ENSG00000072134ENST00000395618O95208
ENSG00000072134ENST00000395620O95208
ENSG00000072134ENST00000395626E9PBC1
ENSG00000072134ENST00000395628F6PQP6
ENSG00000072134ENST00000494192I3L356
ENSG00000072134ENST00000571254I3L2B2
ENSG00000072134ENST00000575595I3L2H1
ENSG00000072134ENST00000577195J3KSA6
ENSG00000072134ENST00000577692J3QLN2
ENSG00000072134ENST00000580579J3QQJ8
ENSG00000072134ENST00000581024J3KTF6
ENSG00000072134ENST00000582015J3KSF8
ENSG00000072134ENST00000583197J3QKL8
ENSG00000072134ENST00000584150J3KSR0
ENSG00000072134ENST00000584633J3KSC7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Clathrin-mediated endocytosisREACTOMER-HSA-8856828
Cargo recognition for clathrin-mediated endocytosisREACTOMER-HSA-8856825

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
287172252017A mammalian mirtron miR-1224 promotes tube-formation of human primary endothelial cells by targeting anti-angiogenic factor epsin2.5
287172252017A mammalian mirtron miR-1224 promotes tube-formation of human primary endothelial cells by targeting anti-angiogenic factor epsin2.5
258710092015Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.19
258710092015Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.19
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

EPN2 (epsin 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/55609/css/js/lib/zoomerang.js