ARHGAP30 (Rho GTPase activating protein 30)

2015-03-01  

Identity

HGNC
ARHGAP30
LOCATION
1q23.3
LOCUSID
257106
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 257106
MIM: 614264
HGNC: 27414
Ensembl: ENSG00000186517

Variants:

dbSNP: 257106
ClinVar: 257106
TCGA: ENSG00000186517
COSMIC: ARHGAP30

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186517ENST00000368013Q7Z6I6
ENSG00000186517ENST00000368015A0A0A0MRJ8
ENSG00000186517ENST00000368016A0A0A0MRJ9
ENSG00000186517ENST00000368018E9PAN4
ENSG00000186517ENST00000471492E9PLA4
ENSG00000186517ENST00000490279E9PLT5

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
371709152023Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway.0
371709152023Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway.0
344906912021Overexpression of ARHGAP30 suppresses growth of cervical cancer cells by downregulating ribosome biogenesis.8
344906912021Overexpression of ARHGAP30 suppresses growth of cervical cancer cells by downregulating ribosome biogenesis.8
324166892020Potential Prognostic Predictors and Molecular Targets for Skin Melanoma Screened by Weighted Gene Co-expression Network Analysis.7
324166892020Potential Prognostic Predictors and Molecular Targets for Skin Melanoma Screened by Weighted Gene Co-expression Network Analysis.7
251564932014ArhGAP30 promotes p53 acetylation and function in colorectal cancer.38
251564932014ArhGAP30 promotes p53 acetylation and function in colorectal cancer.38
215651752011ARHGAP30 is a Wrch-1-interacting protein involved in actin dynamics and cell adhesion.20
215651752011ARHGAP30 is a Wrch-1-interacting protein involved in actin dynamics and cell adhesion.20

Citation

Dessen P

ARHGAP30 (Rho GTPase activating protein 30)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55637/gene-explorer/teaching-explorer/gene-fusions-explorer/