ARPIN (actin related protein 2/3 complex inhibitor)

2015-03-01  

Identity

HGNC
ARPIN
LOCATION
15q26.1
LOCUSID
348110
ALIAS
C15orf38

Other Information

Locus ID:

NCBI: 348110
MIM: 615543
HGNC: 28782
Ensembl: ENSG00000242498

Variants:

dbSNP: 348110
ClinVar: 348110
TCGA: ENSG00000242498
COSMIC: ARPIN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000242498ENST00000357484Q7Z6K5
ENSG00000242498ENST00000460685H0YMP5
ENSG00000242498ENST00000560096H0YL03

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
369219922023RNA Editing Enzyme ADAR1 Suppresses the Mobility of Cancer Cells via ARPIN.2
369219922023RNA Editing Enzyme ADAR1 Suppresses the Mobility of Cancer Cells via ARPIN.2
339234432021Arpin Regulates Migration Persistence by Interacting with Both Tankyrases and the Arp2/3 Complex.5
339234432021Arpin Regulates Migration Persistence by Interacting with Both Tankyrases and the Arp2/3 Complex.5
317214152020Arpin is critical for phagocytosis in macrophages and is targeted by human rhinovirus.9
317214152020Arpin is critical for phagocytosis in macrophages and is targeted by human rhinovirus.9
282930922017Clinicopathological and prognostic significance of aberrant Arpin expression in gastric cancer.3
285318002017Restoration of Arpin suppresses aggressive phenotype of breast cancer cells.3
282930922017Clinicopathological and prognostic significance of aberrant Arpin expression in gastric cancer.3
285318002017Restoration of Arpin suppresses aggressive phenotype of breast cancer cells.3
266485692016Aberrant expression of Arpin in human breast cancer and its clinical significance.6
267741282016Hybrid Structural Analysis of the Arp2/3 Regulator Arpin Identifies Its Acidic Tail as a Primary Binding Epitope.10
266485692016Aberrant expression of Arpin in human breast cancer and its clinical significance.6
267741282016Hybrid Structural Analysis of the Arp2/3 Regulator Arpin Identifies Its Acidic Tail as a Primary Binding Epitope.10
258928812015Arpin contributes to bacterial translocation and development of severe acute pancreatitis.10

Citation

Dessen P

ARPIN (actin related protein 2/3 complex inhibitor)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55646/tumors-explorer/js/lib/gene-fusions-explorer/