MYO1B (myosin IB)

2015-03-01  

Identity

HGNC
MYO1B
LOCATION
2q32.3
LOCUSID
4430
ALIAS
MMI-alpha,MMIa,MYH-1c,myr1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4430
MIM: 606537
HGNC: 7596
Ensembl: ENSG00000128641

Variants:

dbSNP: 4430
ClinVar: 4430
TCGA: ENSG00000128641
COSMIC: MYO1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128641ENST00000304164O43795
ENSG00000128641ENST00000304164B0I1S9
ENSG00000128641ENST00000339514O43795
ENSG00000128641ENST00000392316E9PDF6
ENSG00000128641ENST00000392318O43795
ENSG00000128641ENST00000392318B0I1S9
ENSG00000128641ENST00000418908C9JYW1
ENSG00000128641ENST00000420448C9K0I9
ENSG00000128641ENST00000427152H7C2Y7
ENSG00000128641ENST00000438652C9JUP5
ENSG00000128641ENST00000451437E7EQD9
ENSG00000128641ENST00000634375A0A0U1RRI3

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
366547822023Myo1b Promotes Premature Endothelial Senescence and Dysfunction via Suppressing Autophagy: Implications for Vascular Aging.0
370141562023MYO1B as a prognostic biomarker and a therapeutic target in Arecoline-associated oral carcinoma.1
374816372023CCND1-associated ceRNA network reveal the critical pathway of TPRG1-AS1-hsa-miR-363-3p-MYO1B as a prognostic marker for head and neck squamous cell carcinoma.6
366547822023Myo1b Promotes Premature Endothelial Senescence and Dysfunction via Suppressing Autophagy: Implications for Vascular Aging.0
370141562023MYO1B as a prognostic biomarker and a therapeutic target in Arecoline-associated oral carcinoma.1
374816372023CCND1-associated ceRNA network reveal the critical pathway of TPRG1-AS1-hsa-miR-363-3p-MYO1B as a prognostic marker for head and neck squamous cell carcinoma.6
358619392022Targeting MYO1B impairs tumorigenesis via inhibiting the SNAI2/cyclin D1 signaling in esophageal squamous cell carcinoma.2
363478352022Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer.8
358619392022Targeting MYO1B impairs tumorigenesis via inhibiting the SNAI2/cyclin D1 signaling in esophageal squamous cell carcinoma.2
363478352022Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer.8
304811622019Splicing factor SRSF1 promotes gliomagenesis via oncogenic splice-switching of MYO1B.71
310402422019Toxoplasma Controls Host Cyclin E Expression through the Use of a Novel MYR1-Dependent Effector Protein, HCE1.32
317293652019Myosin 1b is an actin depolymerase.10
304811622019Splicing factor SRSF1 promotes gliomagenesis via oncogenic splice-switching of MYO1B.71
310402422019Toxoplasma Controls Host Cyclin E Expression through the Use of a Novel MYR1-Dependent Effector Protein, HCE1.32

Citation

Dessen P

MYO1B (myosin IB)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55662/css/lib/favicon/haematological-explorer/