NETO2 (neuropilin and tolloid like 2)

2016-08-01 Affiliation

Identity

HGNC

NETO2

LOCATION

16q12.1

LOCUSID

81831

ALIAS

BTCL2,NEOT2

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 81831
MIM: 607974
HGNC: 14644
Ensembl: ENSG00000171208

Variants:

dbSNP: 81831
ClinVar: 81831
TCGA: ENSG00000171208
COSMIC: NETO2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000171208	ENST00000303155	Q8NC67
ENSG00000171208	ENST00000562435	Q8NC67
ENSG00000171208	ENST00000562559	H3BM37
ENSG00000171208	ENST00000563078	H3BSR0
ENSG00000171208	ENST00000564667	H3BTE1

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
36639372	2023	Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth.	3
36738427	2023	NETO2 promotes melanoma progression via activation of the Ca(2+)/CaMKII signaling pathway.	0
36639372	2023	Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth.	3
36738427	2023	NETO2 promotes melanoma progression via activation of the Ca(2+)/CaMKII signaling pathway.	0
33157203	2021	Neuropilin and tolloid-like 2 regulates the progression of osteosarcoma.	3
33390848	2021	NETO2 promotes esophageal cancer progression by inducing proliferation and metastasis via PI3K/AKT and ERK pathway.	21
34552241	2021	Kainate receptor modulation by NETO2.	9
33157203	2021	Neuropilin and tolloid-like 2 regulates the progression of osteosarcoma.	3
33390848	2021	NETO2 promotes esophageal cancer progression by inducing proliferation and metastasis via PI3K/AKT and ERK pathway.	21
34552241	2021	Kainate receptor modulation by NETO2.	9
30770791	2019	NETO2 promotes invasion and metastasis of gastric cancer cells via activation of PI3K/Akt/NF-κB/Snail axis and predicts outcome of the patients.	29
30975469	2019	Reducing NETO2 expression prevents human nasopharyngeal carcinoma (NPC) progression by suppressing metastasis and inducing apoptosis.	3
30770791	2019	NETO2 promotes invasion and metastasis of gastric cancer cells via activation of PI3K/Akt/NF-κB/Snail axis and predicts outcome of the patients.	29
30975469	2019	Reducing NETO2 expression prevents human nasopharyngeal carcinoma (NPC) progression by suppressing metastasis and inducing apoptosis.	3
29989576	2018	[Transcription Factor SAP30 Is Involved in the Activation of NETO2 Gene Expression in Clear Cell Renal Cell Carcinoma].	8

Citation

Dessen P

NETO2 (neuropilin and tolloid like 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55913/gene-fusions-explorer/favicon/manifest.json