CNPY2 (canopy FGF signaling regulator 2)

2016-09-01 Affiliation

Identity

HGNC

CNPY2

LOCATION

12q13.3

LOCUSID

10330

ALIAS

HP10390,MSAP,TMEM4,ZSIG9

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 10330
MIM: 605861
HGNC: 13529
Ensembl: ENSG00000257727

Variants:

dbSNP: 10330
ClinVar: 10330
TCGA: ENSG00000257727
COSMIC: CNPY2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000257727	ENST00000273308	Q9Y2B0
ENSG00000257727	ENST00000546466	H0YI18
ENSG00000257727	ENST00000551286	F8W1K5
ENSG00000257727	ENST00000551475	F8VXJ7
ENSG00000257727	ENST00000553191	H0YIH9

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
33482578	2021	Sleeping Beauty insertional mutagenesis screen identifies the pro-metastatic roles of CNPY2 and ACTN2 in hepatocellular carcinoma tumor progression.	8
33721832	2021	Hypoxia-induced CNPY2 upregulation promotes glycolysis in cervical cancer through activation of AKT pathway.	6
33482578	2021	Sleeping Beauty insertional mutagenesis screen identifies the pro-metastatic roles of CNPY2 and ACTN2 in hepatocellular carcinoma tumor progression.	8
33721832	2021	Hypoxia-induced CNPY2 upregulation promotes glycolysis in cervical cancer through activation of AKT pathway.	6
31894275	2020	miR‑30a‑3p suppresses the proliferation and migration of lung adenocarcinoma cells by downregulating CNPY2.	12
31894275	2020	miR‑30a‑3p suppresses the proliferation and migration of lung adenocarcinoma cells by downregulating CNPY2.	12
31047986	2019	Knockout of Canopy 2 activates p16(INK4a) pathway to impair cardiac repair.	4
31047986	2019	Knockout of Canopy 2 activates p16(INK4a) pathway to impair cardiac repair.	4
29569784	2018	The CNPY2 enhances epithelial-mesenchymal transition via activating the AKT/GSK3β pathway in non-small cell lung cancer.	6
29864955	2018	CNPY2 enhances resistance to apoptosis induced by cisplatin via activation of NF-κB pathway in human non-small cell lung cancer.	3
30070972	2018	Serum CNPY2 isoform 2 represents a novel biomarker for early detection of colorectal cancer.	6
30415246	2018	Canopy Homolog 2 Expression Predicts Poor Prognosis in Hepatocellular Carcinoma with Tumor Hemorrhage.	3
29569784	2018	The CNPY2 enhances epithelial-mesenchymal transition via activating the AKT/GSK3β pathway in non-small cell lung cancer.	6
29864955	2018	CNPY2 enhances resistance to apoptosis induced by cisplatin via activation of NF-κB pathway in human non-small cell lung cancer.	3
30070972	2018	Serum CNPY2 isoform 2 represents a novel biomarker for early detection of colorectal cancer.	6

Citation

Dessen P

CNPY2 (canopy FGF signaling regulator 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-09-01

Online version: http://atlasgeneticsoncology.org/gene/55945