BTBD10 (BTB domain containing 10)

2016-10-01 Affiliation

Identity

HGNC

BTBD10

LOCATION

11p15.3

LOCUSID

84280

ALIAS

GMRP-1,GMRP1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 84280
MIM: 615933
HGNC: 21445
Ensembl: ENSG00000148925

Variants:

dbSNP: 84280
ClinVar: 84280
TCGA: ENSG00000148925
COSMIC: BTBD10

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000148925	ENST00000278174	Q9BSF8
ENSG00000148925	ENST00000278174	D3DQW7
ENSG00000148925	ENST00000525108	E9PN21
ENSG00000148925	ENST00000526841	E9PKM7
ENSG00000148925	ENST00000527102	E9PKU9
ENSG00000148925	ENST00000528120	B7Z503
ENSG00000148925	ENST00000529708	E9PPD8
ENSG00000148925	ENST00000530907	Q9BSF8

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
23320755	2013	Reduced expression of BTBD10 in anterior horn cells with Golgi fragmentation and pTDP-43-positive inclusions in patients with sporadic amyotrophic lateral sclerosis.	5
23320755	2013	Reduced expression of BTBD10 in anterior horn cells with Golgi fragmentation and pTDP-43-positive inclusions in patients with sporadic amyotrophic lateral sclerosis.	5
22388351	2012	Reduced expression of BTBD10, an Akt activator, leads to motor neuron death.	16
22388351	2012	Reduced expression of BTBD10, an Akt activator, leads to motor neuron death.	16
21267538	2011	Glucose metabolism-related protein 1 (GMRP1) regulates pancreatic beta cell proliferation and apoptosis via activation of Akt signalling pathway in rats and mice.	13
21267538	2011	Glucose metabolism-related protein 1 (GMRP1) regulates pancreatic beta cell proliferation and apoptosis via activation of Akt signalling pathway in rats and mice.	13
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
18160256	2008	A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB.	15
18160256	2008	A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB.	15

Citation

Dessen P

BTBD10 (BTB domain containing 10)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/55975/favicon/tumors-explorer/css/lib/dataTables.bootstrap.min.css