REG3G (regenerating family member 3 gamma)

2016-10-01  

Identity

HGNC
REG3G
LOCATION
2p12
LOCUSID
130120
ALIAS
LPPM429,PAP

Other Information

Locus ID:

NCBI: 130120
MIM: 609933
HGNC: 29595
Ensembl: ENSG00000143954

Variants:

dbSNP: 130120
ClinVar: 130120
TCGA: ENSG00000143954
COSMIC: REG3G

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143954ENST00000272324Q6UW15
ENSG00000143954ENST00000393897Q6UW15
ENSG00000143954ENST00000409471Q6UW15

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900
1000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Antimicrobial peptidesREACTOMER-HSA-6803157

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
339237742021Myocardial Accumulations of Reg3A, Reg3γ and Oncostatin M Are Associated with the Formation of Granulomata in Patients with Cardiac Sarcoidosis.5
339237742021Myocardial Accumulations of Reg3A, Reg3γ and Oncostatin M Are Associated with the Formation of Granulomata in Patients with Cardiac Sarcoidosis.5
317679342020Proteasome-dependent degradation of Smad7 is critical for lung cancer metastasis.23
329356612020Role of oncogenic REGγ in cancer.1
317679342020Proteasome-dependent degradation of Smad7 is critical for lung cancer metastasis.23
329356612020Role of oncogenic REGγ in cancer.1
223124302012Helicobacter pylori CagA triggers expression of the bactericidal lectin REG3γ via gastric STAT3 activation.31
223124302012Helicobacter pylori CagA triggers expression of the bactericidal lectin REG3γ via gastric STAT3 activation.31
169317622006Symbiotic bacteria direct expression of an intestinal bactericidal lectin.630
169317622006Symbiotic bacteria direct expression of an intestinal bactericidal lectin.630
157776172005PAP IB, a new member of the Reg gene family: cloning, expression, structural properties, and evolution by gene duplication.11
157776172005PAP IB, a new member of the Reg gene family: cloning, expression, structural properties, and evolution by gene duplication.11
155563042004Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III.25
155563042004Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III.25

Citation

Dessen P

REG3G (regenerating family member 3 gamma)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56210