EMX1 (empty spiracles homeobox 1)

2016-10-01  

Identity

HGNC
EMX1
LOCATION
2p13.2
LOCUSID
2016
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2016
MIM: 600034
HGNC: 3340
Ensembl: ENSG00000135638

Variants:

dbSNP: 2016
ClinVar: 2016
TCGA: ENSG00000135638
COSMIC: EMX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135638ENST00000258106Q04741
ENSG00000135638ENST00000394111A0A087WZF2
ENSG00000135638ENST00000473732F8W1B5

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
384468492024Generation of human excitatory forebrain neurons by cooperative binding of proneural NGN2 and homeobox factor EMX1.1
384468492024Generation of human excitatory forebrain neurons by cooperative binding of proneural NGN2 and homeobox factor EMX1.1
358490302022EMX1 functions as a tumor inhibitor in spinal cord glioma through transcriptional suppression of WASF2 and inactivation of the Wnt/β-catenin axis.1
358490302022EMX1 functions as a tumor inhibitor in spinal cord glioma through transcriptional suppression of WASF2 and inactivation of the Wnt/β-catenin axis.1
340169582021Regulation of sarcomagenesis by the empty spiracles homeobox genes EMX1 and EMX2.10
343643912021Empty spiracles homeobox genes EMX1 and EMX2 regulate WNT pathway activation in sarcomagenesis.6
340169582021Regulation of sarcomagenesis by the empty spiracles homeobox genes EMX1 and EMX2.10
343643912021Empty spiracles homeobox genes EMX1 and EMX2 regulate WNT pathway activation in sarcomagenesis.6
200161092009Emx1-lineage progenitors differentially contribute to neural diversity in the striatum and amygdala.27
200161092009Emx1-lineage progenitors differentially contribute to neural diversity in the striatum and amygdala.27

Citation

Dessen P

EMX1 (empty spiracles homeobox 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56214/meetings/teaching-explorer/deep-insight-explorer/