BET1 (Bet1 golgi vesicular membrane trafficking protein)

2016-10-01  

Identity

HGNC
BET1
LOCATION
7q21.3
LOCUSID
10282
ALIAS
HBET1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10282
MIM: 605456
HGNC: 14562
Ensembl: ENSG00000105829

Variants:

dbSNP: 10282
ClinVar: 10282
TCGA: ENSG00000105829
COSMIC: BET1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105829ENST00000222547O15155
ENSG00000105829ENST00000222547Q53XK0
ENSG00000105829ENST00000357520Q68DU7
ENSG00000105829ENST00000425626C9JTT8
ENSG00000105829ENST00000433727O15155
ENSG00000105829ENST00000457139H7C1N3
ENSG00000105829ENST00000650276A0A3B3IU16

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
SNARE interactions in vesicular transportKEGGko04130
SNARE interactions in vesicular transportKEGGhsa04130
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
COPII (Coat Protein 2) Mediated Vesicle TransportREACTOMER-HSA-204005
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
COPI-mediated anterograde transportREACTOMER-HSA-6807878

References

Pubmed IDYearTitleCitations
364041342023Large-scale genetic screens identify BET-1 as a cytoskeleton regulator promoting actin function and life span.4
364041342023Large-scale genetic screens identify BET-1 as a cytoskeleton regulator promoting actin function and life span.4
347795862021BET1 variants establish impaired vesicular transport as a cause for muscular dystrophy with epilepsy.9
347795862021BET1 variants establish impaired vesicular transport as a cause for muscular dystrophy with epilepsy.9
315197272019MT1-MMP recruits the ER-Golgi SNARE Bet1 for efficient MT1-MMP transport to the plasma membrane.9
315197272019MT1-MMP recruits the ER-Golgi SNARE Bet1 for efficient MT1-MMP transport to the plasma membrane.9
86214311996Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus.34
86214311996Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus.34

Citation

Dessen P

BET1 (Bet1 golgi vesicular membrane trafficking protein)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56255