CATSPER1 (cation channel sperm associated 1)

2016-10-01  

Identity

HGNC
CATSPER1
LOCATION
11q13.1
LOCUSID
117144
ALIAS
CATSPER,SPGF7
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 117144
MIM: 606389
HGNC: 17116
Ensembl: ENSG00000175294

Variants:

dbSNP: 117144
ClinVar: 117144
TCGA: ENSG00000175294
COSMIC: CATSPER1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175294ENST00000312106Q8NEC5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
ReproductionREACTOMER-HSA-1474165
FertilizationREACTOMER-HSA-1187000
Sperm Motility And TaxesREACTOMER-HSA-1300642

References

Pubmed IDYearTitleCitations
383352612024Both protein and non-protein components in extracellular vesicles of human seminal plasma improve human sperm function via CatSper-mediated calcium signaling.1
383662012024Flagellar pH homeostasis mediated by Na+/H+ exchangers regulates human sperm functions through coupling with CatSper and KSper activation.1
383352612024Both protein and non-protein components in extracellular vesicles of human seminal plasma improve human sperm function via CatSper-mediated calcium signaling.1
383662012024Flagellar pH homeostasis mediated by Na+/H+ exchangers regulates human sperm functions through coupling with CatSper and KSper activation.1
334565752021Roles of CatSper channels in the pathogenesis of asthenozoospermia and the therapeutic effects of acupuncture-like treatment on asthenozoospermia.14
344407242021CRISP2, CATSPER1 and PATE1 Expression in Human Asthenozoospermic Semen.7
334565752021Roles of CatSper channels in the pathogenesis of asthenozoospermia and the therapeutic effects of acupuncture-like treatment on asthenozoospermia.14
344407242021CRISP2, CATSPER1 and PATE1 Expression in Human Asthenozoospermic Semen.7
327123862020CatSper: The complex main gate of calcium entry in mammalian spermatozoa.25
327123862020CatSper: The complex main gate of calcium entry in mammalian spermatozoa.25
302035452019Tyrosine phosphorylation signaling regulates Ca(2+) entry by affecting intracellular pH during human sperm capacitation.15
302035452019Tyrosine phosphorylation signaling regulates Ca(2+) entry by affecting intracellular pH during human sperm capacitation.15
300172332018Human CATSPER1 Promoter Is Regulated by CREB1 and CREMτ Transcriptional Factors In Vitro.4
303798602018Regulation of CATSPER1 expression by the testis-determining gene SRY.3
300172332018Human CATSPER1 Promoter Is Regulated by CREB1 and CREMτ Transcriptional Factors In Vitro.4

Citation

Dessen P

CATSPER1 (cation channel sperm associated 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56291