DAGLB (diacylglycerol lipase beta)

2016-10-01  

Identity

HGNC
LOCATION
7p22.1
LOCUSID
ALIAS
DAGLBETA,KCCR13L
FUSION GENES

Other Information

Locus ID:

NCBI: 221955
MIM: 614016
HGNC: 28923
Ensembl: ENSG00000164535

Variants:

dbSNP: 221955
ClinVar: 221955
TCGA: ENSG00000164535
COSMIC: DAGLB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164535ENST00000297056Q8NCG7
ENSG00000164535ENST00000425398Q8NCG7
ENSG00000164535ENST00000432248C9JA85
ENSG00000164535ENST00000436575E7ET49
ENSG00000164535ENST00000454738F8WBN0

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Retrograde endocannabinoid signalingKEGGhsa04723
Retrograde endocannabinoid signalingKEGGko04723
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Effects of PIP2 hydrolysisREACTOMER-HSA-114508
Arachidonate production from DAGREACTOMER-HSA-426048
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907
Aldosterone synthesis and secretionKEGGhsa04925
Aldosterone synthesis and secretionKEGGko04925

References

Pubmed IDYearTitleCitations
294761672018A novel variant associated with HDL-C levels by modifying DAGLB expression levels: An annotation-based genome-wide association study.5
294761672018A novel variant associated with HDL-C levels by modifying DAGLB expression levels: An annotation-based genome-wide association study.5
271157112016Assay and Inhibition of the Purified Catalytic Domain of Diacylglycerol Lipase Beta.0
271157112016Assay and Inhibition of the Purified Catalytic Domain of Diacylglycerol Lipase Beta.0
146100532003Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain.403
146100532003Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain.403

Citation

Dessen P

DAGLB (diacylglycerol lipase beta)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56298/gene-fusions/js/lib/favicon/apple-touch-icon.png