Identity
HGNC
LOCATION
5q35.3
LOCUSID
ALIAS
ADAM-TS2,ADAMTS-2,ADAMTS-3,EDSDERMS,NPI,PC
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9509
MIM: 604539
HGNC: 218
Ensembl: ENSG00000087116
Variants:
dbSNP: 9509
ClinVar: 9509
TCGA: ENSG00000087116
COSMIC: ADAMTS2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000087116 | ENST00000251582 | O95450 |
| ENSG00000087116 | ENST00000274609 | O95450 |
| ENSG00000087116 | ENST00000518335 | A0A1B0GTY3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37929635 | 2024 | Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function. | 1 |
| 37929635 | 2024 | Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function. | 1 |
| 36602125 | 2023 | Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci. | 1 |
| 36602125 | 2023 | Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci. | 1 |
| 36124393 | 2022 | Mutations in the TBX15-ADAMTS2 pathway associate with a novel soft palate dysplasia. | 1 |
| 36124393 | 2022 | Mutations in the TBX15-ADAMTS2 pathway associate with a novel soft palate dysplasia. | 1 |
| 32817637 | 2020 | ADAMTS12, a new candidate gene for pediatric stroke. | 7 |
| 32817637 | 2020 | ADAMTS12, a new candidate gene for pediatric stroke. | 7 |
| 31740729 | 2019 | Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics. | 11 |
| 31804359 | 2019 | Prenatal diagnosis of a 5q35.3 microduplication involving part of the ADAMTS2 locus: a likely benign variant without apparent phenotypic abnormality: Case series. | 1 |
| 31740729 | 2019 | Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics. | 11 |
| 31804359 | 2019 | Prenatal diagnosis of a 5q35.3 microduplication involving part of the ADAMTS2 locus: a likely benign variant without apparent phenotypic abnormality: Case series. | 1 |
| 30388611 | 2018 | The role of ADAMTS-2, collagen type-1, TIMP-3 and papilin levels of uterosacral and cardinal ligaments in the etiopathogenesis of pelvic organ prolapse among women without stress urinary incontinence. | 4 |
| 30388611 | 2018 | The role of ADAMTS-2, collagen type-1, TIMP-3 and papilin levels of uterosacral and cardinal ligaments in the etiopathogenesis of pelvic organ prolapse among women without stress urinary incontinence. | 4 |
| 26765342 | 2016 | Expanding the clinical and mutational spectrum of the Ehlers-Danlos syndrome, dermatosparaxis type. | 17 |
Citation
Dessen P
ADAMTS2 (ADAM metallopeptidase with thrombospondin type 1 motif 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56454/adamts2
