SNAP29 (synaptosome associated protein 29)

2016-10-01  

Identity

HGNC
SNAP29
LOCATION
22q11.21
LOCUSID
9342
ALIAS
CEDNIK,SNAP-29
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9342
MIM: 604202
HGNC: 11133
Ensembl: ENSG00000099940

Variants:

dbSNP: 9342
ClinVar: 9342
TCGA: ENSG00000099940
COSMIC: SNAP29

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000099940ENST00000215730O95721
ENSG00000099940ENST00000439214C9JAF7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
SNARE interactions in vesicular transportKEGGko04130
Autophagy - animalKEGGko04140
SNARE interactions in vesicular transportKEGGhsa04130
Autophagy - animalKEGGhsa04140
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Intra-Golgi trafficREACTOMER-HSA-6811438
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383403172024Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion.2
383403172024Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion.2
352562752023Snapshots from within the cell: Novel trafficking and non trafficking functions of Snap29 during tissue morphogenesis.3
361814142023SNARE-binding protein synaptosomal-associated protein of 29 kDa (SNAP29) regulates the intracellular sequestration of glucose transporter 4 (GLUT4) vesicles in adipocytes.1
352562752023Snapshots from within the cell: Novel trafficking and non trafficking functions of Snap29 during tissue morphogenesis.3
361814142023SNARE-binding protein synaptosomal-associated protein of 29 kDa (SNAP29) regulates the intracellular sequestration of glucose transporter 4 (GLUT4) vesicles in adipocytes.1
340698722021Generation and Characterization of a CRISPR/Cas9-Mediated SNAP29 Knockout in Human Fibroblasts.6
345356382021Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion.32
340698722021Generation and Characterization of a CRISPR/Cas9-Mediated SNAP29 Knockout in Human Fibroblasts.6
345356382021Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion.32
318118992020Silencing DAPK3 blocks the autophagosome-lysosome fusion by mediating SNAP29 in trophoblast cells under high glucose treatment.10
328174232020Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion.11
318118992020Silencing DAPK3 blocks the autophagosome-lysosome fusion by mediating SNAP29 in trophoblast cells under high glucose treatment.10
328174232020Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion.11
307427752019Synaptosomal-associated protein 29 is required for the autophagic degradation of hepatitis B virus.17

Citation

Dessen P

SNAP29 (synaptosome associated protein 29)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56477