Identity
HGNC
LOCATION
12q13.13
LOCUSID
ALIAS
ACTRIB,ACVRLK4,ALK4,SKR2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 91
MIM: 601300
HGNC: 172
Ensembl: ENSG00000135503
Variants:
dbSNP: 91
ClinVar: 91
TCGA: ENSG00000135503
COSMIC: ACVR1B
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36403856 | 2023 | Activin receptor ALK4 promotes adipose tissue hyperplasia by suppressing differentiation of adipocyte precursors. | 2 |
| 37020544 | 2023 | Abundance of ACVR1B transcript is elevated during septic conditions: Perspectives obtained from a hands-on reductionist investigation. | 0 |
| 36403856 | 2023 | Activin receptor ALK4 promotes adipose tissue hyperplasia by suppressing differentiation of adipocyte precursors. | 2 |
| 37020544 | 2023 | Abundance of ACVR1B transcript is elevated during septic conditions: Perspectives obtained from a hands-on reductionist investigation. | 0 |
| 35323108 | 2022 | Lack of Tgfbr1 and Acvr1b synergistically stimulates myofibre hypertrophy and accelerates muscle regeneration. | 6 |
| 35323108 | 2022 | Lack of Tgfbr1 and Acvr1b synergistically stimulates myofibre hypertrophy and accelerates muscle regeneration. | 6 |
| 33230889 | 2021 | Activin A increases human trophoblast invasion by upregulating integrin β1 through ALK4. | 14 |
| 34666056 | 2021 | Implication of rare genetic variants of NODAL and ACVR1B in congenital heart disease patients from Indian population. | 1 |
| 33230889 | 2021 | Activin A increases human trophoblast invasion by upregulating integrin β1 through ALK4. | 14 |
| 34666056 | 2021 | Implication of rare genetic variants of NODAL and ACVR1B in congenital heart disease patients from Indian population. | 1 |
| 31982478 | 2020 | ALK4-SMAD3/4 mediates the effects of activin A on the upregulation of PAI-1 in human granulosa lutein cells. | 3 |
| 31990347 | 2020 | Alterations in activin A-myostatin-follistatin system associate with disease activity in inflammatory myopathies. | 9 |
| 33342936 | 2020 | [Involvement of Notch1 and ALK4/5 Signaling Pathways in Renal Tubular Cell Death: Their Application to Clarification of Cadmium Toxicity]. | 0 |
| 31982478 | 2020 | ALK4-SMAD3/4 mediates the effects of activin A on the upregulation of PAI-1 in human granulosa lutein cells. | 3 |
| 31990347 | 2020 | Alterations in activin A-myostatin-follistatin system associate with disease activity in inflammatory myopathies. | 9 |
Citation
Dessen P
ACVR1B (activin A receptor type 1B)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/565/acvr1b
