TECPR1 (tectonin beta-propeller repeat containing 1)

2016-10-01  

Identity

HGNC
TECPR1
LOCATION
7q21.3
LOCUSID
25851
ALIAS
-

Other Information

Locus ID:

NCBI: 25851
MIM: 614781
HGNC: 22214
Ensembl: ENSG00000205356

Variants:

dbSNP: 25851
ClinVar: 25851
TCGA: ENSG00000205356
COSMIC: TECPR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205356ENST00000415086C9J2A1
ENSG00000205356ENST00000420697C9JEV4
ENSG00000205356ENST00000423128C9JUV4
ENSG00000205356ENST00000447648Q7Z6L1

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
374095252023TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy.13
374095252023TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy.13
361977712022TECPR1 Induces Apoptosis in Non-Small Cell Lung Carcinoma via ATG5 Upregulation-Induced Autophagy Promotion.0
361977712022TECPR1 Induces Apoptosis in Non-Small Cell Lung Carcinoma via ATG5 Upregulation-Induced Autophagy Promotion.0
325329702020TECPR1 promotes aggrephagy by direct recruitment of LC3C autophagosomes to lysosomes.20
325329702020TECPR1 promotes aggrephagy by direct recruitment of LC3C autophagosomes to lysosomes.20
223423422012A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugate.97
223423422012A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugate.97

Citation

Dessen P

TECPR1 (tectonin beta-propeller repeat containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56512