SNAPIN (SNAP associated protein)

2016-10-01  

Identity

HGNC
SNAPIN
LOCATION
1q21.3
LOCUSID
23557
ALIAS
BLOC1S7,BLOS7,BORCS3,SNAPAP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23557
MIM: 607007
HGNC: 17145
Ensembl: ENSG00000143553

Variants:

dbSNP: 23557
ClinVar: 23557
TCGA: ENSG00000143553
COSMIC: SNAPIN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143553ENST00000368685O95295

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
trans-Golgi Network Vesicle BuddingREACTOMER-HSA-199992
Clathrin derived vesicle buddingREACTOMER-HSA-421837
Golgi Associated Vesicle BiogenesisREACTOMER-HSA-432722

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
341943882021SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.4
346819282021Snapin Specifically Up-Regulates Ca(v)1.3 Ca(2+) Channel Variant with a Long Carboxyl Terminus.1
341943882021SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.4
346819282021Snapin Specifically Up-Regulates Ca(v)1.3 Ca(2+) Channel Variant with a Long Carboxyl Terminus.1
279150472017Physical and functional interaction of Snapin with Cav1.3 calcium channel impacts channel protein trafficking in atrial myocytes.7
279297052017SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages.18
289238242017Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling.10
279150472017Physical and functional interaction of Snapin with Cav1.3 calcium channel impacts channel protein trafficking in atrial myocytes.7
279297052017SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages.18
289238242017Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling.10
266879462016Snapin interacts with G-protein coupled receptor PKR2.3
272409782016Host protein Snapin interacts with human cytomegalovirus pUL130 and affects viral DNA replication.5
266879462016Snapin interacts with G-protein coupled receptor PKR2.3
272409782016Host protein Snapin interacts with human cytomegalovirus pUL130 and affects viral DNA replication.5
247514782014Chlamydia psittaci inclusion membrane protein IncB associates with host protein Snapin.11

Citation

Dessen P

SNAPIN (SNAP associated protein)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56558/js/lib/css/deep-insight-explorer/