TBC1D10B (TBC1 domain family member 10B)

2016-10-01  

Identity

HGNC
TBC1D10B
LOCATION
16p11.2
LOCUSID
26000
ALIAS
EPI64B,FP2461
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 26000
MIM: 613620
HGNC: 24510
Ensembl: ENSG00000169221

Variants:

dbSNP: 26000
ClinVar: 26000
TCGA: ENSG00000169221
COSMIC: TBC1D10B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169221ENST00000409939Q4KMP7
ENSG00000169221ENST00000490703H3BSE1

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
TBC/RABGAPsREACTOMER-HSA-8854214

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
347578522022The RabGAPs EPI64A and EPI64B regulate the apical structure of epithelial cells (†).0
347578522022The RabGAPs EPI64A and EPI64B regulate the apical structure of epithelial cells (†).0
323977982020STAT4-mediated down-regulation of miR-3619-5p facilitates stomach adenocarcinoma by modulating TBC1D10B.4
323977982020STAT4-mediated down-regulation of miR-3619-5p facilitates stomach adenocarcinoma by modulating TBC1D10B.4
315277502019Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins.14
315277502019Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins.14
232482412013All members of the EPI64 subfamily of TBC/RabGAPs also have GAP activities towards Ras.6
232482412013All members of the EPI64 subfamily of TBC/RabGAPs also have GAP activities towards Ras.6

Citation

Dessen P

TBC1D10B (TBC1 domain family member 10B)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56583