DZIP3 (DAZ interacting zinc finger protein 3)

2017-04-01  

Identity

HGNC
LOCATION
3q13.13
LOCUSID
ALIAS
PPP1R66,UURF2,hRUL138
FUSION GENES

Other Information

Locus ID:

NCBI: 9666
MIM: 608672
HGNC: 30938
Ensembl: ENSG00000198919

Variants:

dbSNP: 9666
ClinVar: 9666
TCGA: ENSG00000198919
COSMIC: DZIP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198919ENST00000361582Q86Y13
ENSG00000198919ENST00000463306Q86Y13
ENSG00000198919ENST00000479138C9J9M8
ENSG00000198919ENST00000486815C9JRX4
ENSG00000198919ENST00000495008Q86Y13
ENSG00000198919ENST00000497905C9J702

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
368413242023Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.0
368413242023Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.0
330672652021RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression.9
330672652021RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression.9
332296272020DZIP3 is a key factor to stratify IDH1 wild-type lower-grade gliomas.4
332296272020DZIP3 is a key factor to stratify IDH1 wild-type lower-grade gliomas.4
182069702008Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation.176
182069702008Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation.176

Citation

Dessen P

DZIP3 (DAZ interacting zinc finger protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56754/gene-explorer/js/tumors-explorer/