JPT1 (Jupiter microtubule associated homolog 1)

2017-04-01  

Identity

HGNC
JPT1
LOCATION
17q25.1
LOCUSID
51155
ALIAS
ARM2,HN1,HN1A
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51155
HGNC: 14569
Ensembl: ENSG00000189159

Variants:

dbSNP: 51155
ClinVar: 51155
TCGA: ENSG00000189159
COSMIC: JPT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000189159ENST00000304834F2Z3M5
ENSG00000189159ENST00000356033Q9UK76
ENSG00000189159ENST00000409753Q9UK76
ENSG00000189159ENST00000470924Q9UK76
ENSG00000189159ENST00000476258Q9UK76
ENSG00000189159ENST00000481647Q9UK76
ENSG00000189159ENST00000482348Q9UK76
ENSG00000189159ENST00000580380J3KSH8
ENSG00000189159ENST00000581874J3KT51

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
364032812023Hematological and neurological expressed 1 (HN1) activates c-Myc signaling by inhibiting ubiquitin-mediated proteasomal degradation of c-Myc in hepatocellular carcinoma.1
367563862023Thirdhand Smoke May Promote Lung Adenocarcinoma Development through HN1.1
364032812023Hematological and neurological expressed 1 (HN1) activates c-Myc signaling by inhibiting ubiquitin-mediated proteasomal degradation of c-Myc in hepatocellular carcinoma.1
367563862023Thirdhand Smoke May Promote Lung Adenocarcinoma Development through HN1.1
343377142021LncRNA HOXA11-AS promotes cell growth by sponging miR-24-3p to regulate JPT1 in prostate cancer.5
343377142021LncRNA HOXA11-AS promotes cell growth by sponging miR-24-3p to regulate JPT1 in prostate cancer.5
318086202020Jupiter microtubule-associated homolog 1 (JPT1): A predictive and pharmacodynamic biomarker of metformin response in endometrial cancers.6
327007282020HN1 as a diagnostic and prognostic biomarker for liver cancer.2
328283202020HN1 promotes tumor associated lymphangiogenesis and lymph node metastasis via NF-κB signaling activation in cervical carcinoma.8
318086202020Jupiter microtubule-associated homolog 1 (JPT1): A predictive and pharmacodynamic biomarker of metformin response in endometrial cancers.6
327007282020HN1 as a diagnostic and prognostic biomarker for liver cancer.2
328283202020HN1 promotes tumor associated lymphangiogenesis and lymph node metastasis via NF-κB signaling activation in cervical carcinoma.8
312572252019HNRNPA1-mediated 3' UTR length changes of HN1 contributes to cancer- and senescence-associated phenotypes.12
312572252019HNRNPA1-mediated 3' UTR length changes of HN1 contributes to cancer- and senescence-associated phenotypes.12
284903342017HN1 contributes to migration, invasion, and tumorigenesis of breast cancer by enhancing MYC activity.25

Citation

Dessen P

JPT1 (Jupiter microtubule associated homolog 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56784/css/lib/favicon/apple-touch-icon.png