ALKAL1 (ALK and LTK ligand 1)

2017-04-01  

Identity

HGNC
ALKAL1
LOCATION
8q11.23
LOCUSID
389658
ALIAS
AUGA,AUGB,FAM150A,UNQ9433

Other Information

Locus ID:

NCBI: 389658
HGNC: 33775
Ensembl: ENSG00000196711

Variants:

dbSNP: 389658
ClinVar: 389658
TCGA: ENSG00000196711
COSMIC: ALKAL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196711ENST00000358543Q6UXT8
ENSG00000196711ENST00000523939Q6UXT8

Expression (GTEx)

0
1
2
3
4
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
293175322018ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells.42
293175322018ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells.42
264187452015FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase.80
266300102015Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand-receptor interactions.0
264187452015FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase.80
266300102015Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand-receptor interactions.0
253318932014Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome.30
253318932014Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome.30

Citation

Dessen P

ALKAL1 (ALK and LTK ligand 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56836/meetings/img/gene-explorer/