LARP4B (La ribonucleoprotein 4B)

2017-04-01  

Identity

HGNC
LARP4B
LOCATION
10p15.3
LOCUSID
23185
ALIAS
KIAA0217,LARP5
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23185
MIM: 616513
HGNC: 28987
Ensembl: ENSG00000107929

Variants:

dbSNP: 23185
ClinVar: 23185
TCGA: ENSG00000107929
COSMIC: LARP4B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107929ENST00000316157Q92615
ENSG00000107929ENST00000406525B5MCU2
ENSG00000107929ENST00000412411X6RCG6
ENSG00000107929ENST00000440895H0Y641
ENSG00000107929ENST00000448368H0Y4V9
ENSG00000107929ENST00000476529V9GYI5
ENSG00000107929ENST00000614908A0A087X183

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
311732372019MicroRNA‑106b functions as an oncogene and regulates tumor viability and metastasis by targeting LARP4B in prostate cancer.8
317726832019Expression of La Ribonucleoprotein Domain Family Member 4B (LARP4B) in Liver Cancer and Their Clinical and Prognostic Significance.12
311732372019MicroRNA‑106b functions as an oncogene and regulates tumor viability and metastasis by targeting LARP4B in prostate cancer.8
317726832019Expression of La Ribonucleoprotein Domain Family Member 4B (LARP4B) in Liver Cancer and Their Clinical and Prognostic Significance.12
269330872016Identification of RNA-Binding Protein LARP4B as a Tumor Suppressor in Glioma.31
269330872016Identification of RNA-Binding Protein LARP4B as a Tumor Suppressor in Glioma.31
255342022015La-related protein 4B maintains murine MLL-AF9 leukemia stem cell self-renewal by regulating cell cycle progression.9
260017952015LARP4B is an AU-rich sequence associated factor that promotes mRNA accumulation and translation.27
255342022015La-related protein 4B maintains murine MLL-AF9 leukemia stem cell self-renewal by regulating cell cycle progression.9
260017952015LARP4B is an AU-rich sequence associated factor that promotes mRNA accumulation and translation.27
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

LARP4B (La ribonucleoprotein 4B)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56893/js/gene-explorer/gene-fusions-explorer/