CFD (complement factor D)

2017-08-01  

Identity

HGNC
CFD
LOCATION
19p13.3
LOCUSID
1675
ALIAS
ADIPSIN,ADN,DF,PFD
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1675
MIM: 134350
HGNC: 2771
Ensembl: ENSG00000197766

Variants:

dbSNP: 1675
ClinVar: 1675
TCGA: ENSG00000197766
COSMIC: CFD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197766ENST00000327726P00746
ENSG00000197766ENST00000592860K7ERG9

Expression (GTEx)

0
500
1000
1500
2000
2500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Complement and coagulation cascadesKEGGko04610
Complement and coagulation cascadesKEGGhsa04610
Staphylococcus aureus infectionKEGGko05150
Staphylococcus aureus infectionKEGGhsa05150
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Complement cascadeREACTOMER-HSA-166658
Initial triggering of complementREACTOMER-HSA-166663
Alternative complement activationREACTOMER-HSA-173736
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608
Neutrophil degranulationREACTOMER-HSA-6798695

References

Pubmed IDYearTitleCitations
381140422024Adipsin in the pathogenesis of cardiovascular diseases.0
384790052024Combinatorial Inhibition of Complement Factor D and BCL2 for Early-Onset Colorectal Cancer.0
381140422024Adipsin in the pathogenesis of cardiovascular diseases.0
384790052024Combinatorial Inhibition of Complement Factor D and BCL2 for Early-Onset Colorectal Cancer.0
343093312023Long-term physical activity modulates adipsin and ANGPTL4 serum levels, a potential link to exercise-induced metabolic changes.1
364594212023Serum and salivary adipsin levels and its association with insulin resistance in acne vulgaris patients.1
375557342023The Role of Adipsin, Complement Factor D, in the Pathogenesis of Graves' Orbitopathy.1
377443512023Complement factor D regulates collagen type I expression and fibroblast migration to enhance human tendon repair and healing outcomes.1
343093312023Long-term physical activity modulates adipsin and ANGPTL4 serum levels, a potential link to exercise-induced metabolic changes.1
364594212023Serum and salivary adipsin levels and its association with insulin resistance in acne vulgaris patients.1
375557342023The Role of Adipsin, Complement Factor D, in the Pathogenesis of Graves' Orbitopathy.1
377443512023Complement factor D regulates collagen type I expression and fibroblast migration to enhance human tendon repair and healing outcomes.1
352163362022Adipsin Serum Concentrations and Adipose Tissue Expression in People with Obesity and Type 2 Diabetes.11
354369122022Plasma and aqueous levels of alarin and adipsin ın patients with and without diabetic retinopathy.5
355966792022Complement factor D as a predictor of Achilles tendon healing and long-term patient outcomes.6

Citation

Dessen P

CFD (complement factor D)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56965/teaching-explorer/haematological-explorer/css/template-nav.css