PRR14 (proline rich 14)

2017-10-01  

Identity

HGNC
PRR14
LOCATION
16p11.2
LOCUSID
78994
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 78994
MIM: 617423
HGNC: 28458
Ensembl: ENSG00000156858

Variants:

dbSNP: 78994
ClinVar: 78994
TCGA: ENSG00000156858
COSMIC: PRR14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000156858ENST00000300835Q9BWN1
ENSG00000156858ENST00000300835A0A024QZB5
ENSG00000156858ENST00000542965Q9BWN1
ENSG00000156858ENST00000542965A0A024QZB5
ENSG00000156858ENST00000568754H3BND2
ENSG00000156858ENST00000569864H3BQL8

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
323173972020The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting.14
323173972020The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting.14
315968872019PRR14 overexpression promotes cell growth, epithelial to mesenchymal transition and metastasis of colon cancer via the AKT pathway.6
315968872019PRR14 overexpression promotes cell growth, epithelial to mesenchymal transition and metastasis of colon cancer via the AKT pathway.6
270415742016PRR14 is a novel activator of the PI3K pathway promoting lung carcinogenesis.14
270415742016PRR14 is a novel activator of the PI3K pathway promoting lung carcinogenesis.14
259061572015A novel role of PRR14 in the regulation of skeletal myogenesis.12
259061572015A novel role of PRR14 in the regulation of skeletal myogenesis.12
242097422013The human protein PRR14 tethers heterochromatin to the nuclear lamina during interphase and mitotic exit.65
242097422013The human protein PRR14 tethers heterochromatin to the nuclear lamina during interphase and mitotic exit.65

Citation

Dessen P

PRR14 (proline rich 14)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57081