CDC40 (cell division cycle 40)

2017-11-01  

Identity

HGNC
LOCATION
6q21
LOCUSID
ALIAS
EHB3,PCH15,PRP17,PRPF17
FUSION GENES

Other Information

Locus ID:

NCBI: 51362
MIM: 605585
HGNC: 17350
Ensembl: ENSG00000168438

Variants:

dbSNP: 51362
ClinVar: 51362
TCGA: ENSG00000168438
COSMIC: CDC40

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168438ENST00000307731O60508
ENSG00000168438ENST00000368930Q5SRN1
ENSG00000168438ENST00000368932O60508

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Spliceosome, 35S U5-snRNPKEGGhsa_M00355
Spliceosome, 35S U5-snRNPKEGGM00355
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Transcription TerminationREACTOMER-HSA-73856
Cleavage of Growing Transcript in the Termination RegionREACTOMER-HSA-109688
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163
mRNA 3'-end processingREACTOMER-HSA-72187
Transport of Mature Transcript to CytoplasmREACTOMER-HSA-72202
Transport of Mature mRNA derived from an Intron-Containing TranscriptREACTOMER-HSA-159236

References

Pubmed IDYearTitleCitations
273492212016HBx-induced MiR-1269b in NF-κB dependent manner upregulates cell division cycle 40 homolog (CDC40) to promote proliferation and migration in hepatoma cells.19
273492212016HBx-induced MiR-1269b in NF-κB dependent manner upregulates cell division cycle 40 homolog (CDC40) to promote proliferation and migration in hepatoma cells.19
194209642009Somatic mutations of the CDC4 (FBXW7) gene in hereditary colorectal tumors.12
194209642009Somatic mutations of the CDC4 (FBXW7) gene in hereditary colorectal tumors.12

Citation

Dessen P

CDC40 (cell division cycle 40)

Atlas Genet Cytogenet Oncol Haematol. 2017-11-01

Online version: http://atlasgeneticsoncology.org/gene/57247/case-report-explorer/js/lib/css/template-nav.css