COMMD10 (COMM domain containing 10)

2017-11-01 Affiliation

Identity

HGNC

COMMD10

LOCATION

5q23.1

LOCUSID

51397

ALIAS

PTD002

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 51397
MIM: 616704
HGNC: 30201
Ensembl: ENSG00000145781

Variants:

dbSNP: 51397
ClinVar: 51397
TCGA: ENSG00000145781
COSMIC: COMMD10

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000145781	ENST00000274458	Q9Y6G5
ENSG00000145781	ENST00000506589	H0Y9N4
ENSG00000145781	ENST00000507356	D6RC04
ENSG00000145781	ENST00000515539	D6RJ90
ENSG00000145781	ENST00000632434	D6RJ90

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
36919165	2023	Comprehensive analysis of COMMD10 as a novel prognostic biomarker for gastric cancer.	3
36919165	2023	Comprehensive analysis of COMMD10 as a novel prognostic biomarker for gastric cancer.	3
35101526	2022	COMMD10 inhibits HIF1α/CP loop to enhance ferroptosis and radiosensitivity by disrupting Cu-Fe balance in hepatocellular carcinoma.	80
35101526	2022	COMMD10 inhibits HIF1α/CP loop to enhance ferroptosis and radiosensitivity by disrupting Cu-Fe balance in hepatocellular carcinoma.	80
34047468	2021	COMMD10 inhibits tumor progression and induces apoptosis by blocking NF-κB signal and values up BCLC staging in predicting overall survival in hepatocellular carcinoma.	9
34047468	2021	COMMD10 inhibits tumor progression and induces apoptosis by blocking NF-κB signal and values up BCLC staging in predicting overall survival in hepatocellular carcinoma.	9
30787448	2020	Expression profile and bioinformatics analysis of COMMD10 in BALB/C mice and human.	15
30787448	2020	Expression profile and bioinformatics analysis of COMMD10 in BALB/C mice and human.	15
28817833	2017	FMNL2 destabilises COMMD10 to activate NF-κB pathway in invasion and metastasis of colorectal cancer.	21
28817833	2017	FMNL2 destabilises COMMD10 to activate NF-κB pathway in invasion and metastasis of colorectal cancer.	21
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	15
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	15
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	105
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	105

Citation

Dessen P

COMMD10 (COMM domain containing 10)

Atlas Genet Cytogenet Oncol Haematol. 2017-11-01

Online version: http://atlasgeneticsoncology.org/gene/57251/cancer-prone-explorer/haematological-explorer/tumors-explorer/