BZW2 (basic leucine zipper and W2 domains 2)

2018-07-01  

Identity

HGNC
BZW2
LOCATION
7p21.1
LOCUSID
28969
ALIAS
5MP1,HSPC028,MST017,MSTP017
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 28969
HGNC: 18808
Ensembl: ENSG00000136261

Variants:

dbSNP: 28969
ClinVar: 28969
TCGA: ENSG00000136261
COSMIC: BZW2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136261ENST00000258761Q9Y6E2
ENSG00000136261ENST00000258761A0A024RA42
ENSG00000136261ENST00000405202B5MCH7
ENSG00000136261ENST00000407633B5MCE7
ENSG00000136261ENST00000415365E7ETZ4
ENSG00000136261ENST00000430000C9JF98
ENSG00000136261ENST00000433922Q9Y6E2
ENSG00000136261ENST00000433922A0A024RA42
ENSG00000136261ENST00000436868F8WDX8
ENSG00000136261ENST00000437745E9PFE3
ENSG00000136261ENST00000438834E7EMS9
ENSG00000136261ENST00000446596Q75MG1
ENSG00000136261ENST00000452975E9PFD4
ENSG00000136261ENST00000630952E9PFE3

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381546912024Interactome Analysis Identifies the Role of BZW2 in Promoting Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Metabolism.0
385382582024The Prognostic and Immune Significance of BZW2 in Pan-Cancer and its Relationship with Proliferation and Apoptosis of Cervical Cancer.0
381546912024Interactome Analysis Identifies the Role of BZW2 in Promoting Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Metabolism.0
385382582024The Prognostic and Immune Significance of BZW2 in Pan-Cancer and its Relationship with Proliferation and Apoptosis of Cervical Cancer.0
370673402023BZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis.3
372227742023m6A methyltransferase METTL3 facilitates multiple myeloma cell growth through the m6A modification of BZW2.3
370673402023BZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis.3
372227742023m6A methyltransferase METTL3 facilitates multiple myeloma cell growth through the m6A modification of BZW2.3
350683732022miR-140-3p attenuated the tumorigenesis of multiple myeloma via attenuating BZW2.3
350683732022miR-140-3p attenuated the tumorigenesis of multiple myeloma via attenuating BZW2.3
342609312021Human oncoprotein 5MP suppresses general and repeat-associated non-AUG translation via eIF3 by a common mechanism.12
342609312021Human oncoprotein 5MP suppresses general and repeat-associated non-AUG translation via eIF3 by a common mechanism.12
316430922020BZW2 promotes the malignant progression of colorectal cancer via activating the ERK/MAPK pathway.18
316430922020BZW2 promotes the malignant progression of colorectal cancer via activating the ERK/MAPK pathway.18
309323312019BZW2 gene knockdown induces cell growth inhibition, G1 arrest and apoptosis in muscle-invasive bladder cancers: A microarray pathway analysis.12

Citation

Dessen P

BZW2 (basic leucine zipper and W2 domains 2)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57448/js/lib/js/case-report-explorer/