CILP (cartilage intermediate layer protein)

2018-07-01  

Identity

HGNC
CILP
LOCATION
15q22.31
LOCUSID
8483
ALIAS
CILP-1,HsT18872
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8483
MIM: 603489
HGNC: 1980
Ensembl: ENSG00000138615

Variants:

dbSNP: 8483
ClinVar: 8483
TCGA: ENSG00000138615
COSMIC: CILP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138615ENST00000261883O75339

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)REACTOMER-HSA-2404192

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
379683432024CILP is a potential pan-cancer marker: combined silico study and in vitro analyses.0
379683432024CILP is a potential pan-cancer marker: combined silico study and in vitro analyses.0
381321522023CILP-1 Is a Biomarker for Backward Failure and Right Ventricular Dysfunction in HFrEF.1
381321522023CILP-1 Is a Biomarker for Backward Failure and Right Ventricular Dysfunction in HFrEF.1
302886882018Association of CILP, COL9A2 and MMP3 Gene Polymorphisms with Lumbar Disc Degeneration in an Indian Population.6
302886882018Association of CILP, COL9A2 and MMP3 Gene Polymorphisms with Lumbar Disc Degeneration in an Indian Population.6
292330862017Functional polymorphisms in asporin and CILP together with joint loading predispose to hand osteoarthritis.8
292330862017Functional polymorphisms in asporin and CILP together with joint loading predispose to hand osteoarthritis.8
273593562016Association Between Cartilage Intermediate Layer Protein and Degeneration of Intervertebral Disc: A Meta-analysis.8
273593562016Association Between Cartilage Intermediate Layer Protein and Degeneration of Intervertebral Disc: A Meta-analysis.8
221077602011Genetic susceptibility of intervertebral disc degeneration among young Finnish adults.44
221077602011Genetic susceptibility of intervertebral disc degeneration among young Finnish adults.44
207246432010Cartilage intermediate layer protein gene is associated with lumbar disc degeneration in male, but not female, collegiate athletes.12
207246432010Cartilage intermediate layer protein gene is associated with lumbar disc degeneration in male, but not female, collegiate athletes.12
207246432010Cartilage intermediate layer protein gene is associated with lumbar disc degeneration in male, but not female, collegiate athletes.12

Citation

Dessen P

CILP (cartilage intermediate layer protein)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57460