GMFB (glia maturation factor beta)

2018-07-01  

Identity

HGNC
GMFB
LOCATION
14q22.2
LOCUSID
2764
ALIAS
GMF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2764
MIM: 601713
HGNC: 4373
Ensembl: ENSG00000197045

Variants:

dbSNP: 2764
ClinVar: 2764
TCGA: ENSG00000197045
COSMIC: GMFB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197045ENST00000358056P60983
ENSG00000197045ENST00000553333G3V4P8
ENSG00000197045ENST00000554247G3V3X4
ENSG00000197045ENST00000554908G3V3X4
ENSG00000197045ENST00000616146P60983
ENSG00000197045ENST00000628554G3V3X4

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
373078242024G9a Inhibition Promotes Neuroprotection through GMFB Regulation in Alzheimer's Disease.3
382562542024Parkinson's Disease Dementia Patients: Expression of Glia Maturation Factor in the Brain.1
386579212024SUMOylation of GMFB regulates its stability and function in retinal pigment epithelial cells under hyperglycemia.0
373078242024G9a Inhibition Promotes Neuroprotection through GMFB Regulation in Alzheimer's Disease.3
382562542024Parkinson's Disease Dementia Patients: Expression of Glia Maturation Factor in the Brain.1
386579212024SUMOylation of GMFB regulates its stability and function in retinal pigment epithelial cells under hyperglycemia.0
347935512021MicroRNA-5195-3p alleviates high glucose‑induced injury in human ARPE-19 cells by targeting GMFB.5
347935512021MicroRNA-5195-3p alleviates high glucose‑induced injury in human ARPE-19 cells by targeting GMFB.5
291720012018Co-Expression of Glia Maturation Factor and Apolipoprotein E4 in Alzheimer's Disease Brain.18
293836902018Glia Maturation Factor Dependent Inhibition of Mitochondrial PGC-1α Triggers Oxidative Stress-Mediated Apoptosis in N27 Rat Dopaminergic Neuronal Cells.18
291720012018Co-Expression of Glia Maturation Factor and Apolipoprotein E4 in Alzheimer's Disease Brain.18
293836902018Glia Maturation Factor Dependent Inhibition of Mitochondrial PGC-1α Triggers Oxidative Stress-Mediated Apoptosis in N27 Rat Dopaminergic Neuronal Cells.18
265155902016Expressions of glia maturation factor-β by tumor cells and endothelia correlate with neovascularization and poor prognosis in human glioma.5
265155902016Expressions of glia maturation factor-β by tumor cells and endothelia correlate with neovascularization and poor prognosis in human glioma.5
220353522012Expression of glia maturation factor in neuropathological lesions of Alzheimer's disease.38

Citation

Dessen P

GMFB (glia maturation factor beta)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57498