PPIF (peptidylprolyl isomerase F)

2019-04-01  

Identity

HGNC
PPIF
LOCATION
10q22.3
LOCUSID
10105
ALIAS
CYP3,CyP-M,Cyp-D,CypD
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10105
MIM: 604486
HGNC: 9259
Ensembl: ENSG00000108179

Variants:

dbSNP: 10105
ClinVar: 10105
TCGA: ENSG00000108179
COSMIC: PPIF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108179ENST00000225174P30405
ENSG00000108179ENST00000225174A0A024QZS4
ENSG00000108179ENST00000448165H0Y548
ENSG00000108179ENST00000472580R4GN99

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Calcium signaling pathwayKEGGko04020
Huntington's diseaseKEGGko05016
Calcium signaling pathwayKEGGhsa04020
Parkinson's diseaseKEGGhsa05012
Huntington's diseaseKEGGhsa05016
ToxoplasmosisKEGGko05145
ToxoplasmosisKEGGhsa05145
cGMP-PKG signaling pathwayKEGGhsa04022
cGMP-PKG signaling pathwayKEGGko04022

References

Pubmed IDYearTitleCitations
385642922024Role of the mitochondrial protein cyclophilin D in skin wound healing and collagen secretion.0
386390882024Mitochondrial CypD Acetylation Promotes Endothelial Dysfunction and Hypertension.0
385642922024Role of the mitochondrial protein cyclophilin D in skin wound healing and collagen secretion.0
386390882024Mitochondrial CypD Acetylation Promotes Endothelial Dysfunction and Hypertension.0
362739002023Cinnamtannin B-1 Inhibits the Progression of Osteosarcoma by Regulating the miR-1281/PPIF Axis.1
362739002023Cinnamtannin B-1 Inhibits the Progression of Osteosarcoma by Regulating the miR-1281/PPIF Axis.1
334954132021Overexpression of TICRR and PPIF confer poor prognosis in endometrial cancer identified by gene co-expression network analysis.11
346816822021Formation of High-Conductive C Subunit Channels upon Interaction with Cyclophilin D.4
334954132021Overexpression of TICRR and PPIF confer poor prognosis in endometrial cancer identified by gene co-expression network analysis.11
346816822021Formation of High-Conductive C Subunit Channels upon Interaction with Cyclophilin D.4
320419242020microRNA-1203 targets and silences cyclophilin D to protect human endometrial cells from oxygen and glucose deprivation-re-oxygenation.5
322753952020RNase T1 Refolding Assay for Determining Mitochondrial Cyclophilin D Activity: A Novel In Vitro Method Applicable in Drug Research and Discovery.0
320419242020microRNA-1203 targets and silences cyclophilin D to protect human endometrial cells from oxygen and glucose deprivation-re-oxygenation.5
322753952020RNase T1 Refolding Assay for Determining Mitochondrial Cyclophilin D Activity: A Novel In Vitro Method Applicable in Drug Research and Discovery.0
318844212019Targeting cyclophilin-D by miR-1281 protects human macrophages from Mycobacterium tuberculosis-induced programmed necrosis and apoptosis.12

Citation

Dessen P

PPIF (peptidylprolyl isomerase F)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57966