MACROH2A1 (macroH2A.1 histone)

2019-08-01  

Identity

HGNC
MACROH2A1
LOCATION
5q31.1
LOCUSID
9555
ALIAS
H2A.y,H2A/y,H2AF12M,H2AFY,MACROH2A1.1,mH2A1,macroH2A1.2

Other Information

Locus ID:

NCBI: 9555
MIM: 610054
HGNC: 4740
Ensembl: ENSG00000113648

Variants:

dbSNP: 9555
ClinVar: 9555
TCGA: ENSG00000113648
COSMIC: MACROH2A1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000113648ENST00000304332O75367
ENSG00000113648ENST00000312469O75367
ENSG00000113648ENST00000423969B4DJC3
ENSG00000113648ENST00000506671D6RCF2
ENSG00000113648ENST00000510038O75367
ENSG00000113648ENST00000511689O75367

Pathways

PathwaySourceExternal ID
Systemic lupus erythematosusKEGGko05322
Systemic lupus erythematosusKEGGhsa05322
AlcoholismKEGGhsa05034
AlcoholismKEGGko05034

References

Pubmed IDYearTitleCitations
378529772023MacroH2A1.1 as a crossroad between epigenetics, inflammation and metabolism of mesenchymal stromal cells in myelodysplastic syndromes.1
378529772023MacroH2A1.1 as a crossroad between epigenetics, inflammation and metabolism of mesenchymal stromal cells in myelodysplastic syndromes.1
350727992022Analysis of histone variant constraint and tissue expression suggests five potential novel human disease genes: H2AFY2, H2AFZ, H2AFY, H2AFV, H1F0.3
354723082022High expression of H2A histone family member Y promotes the proliferation and autophagy of hepatocellular carcinoma cells.0
355118672022Histone Variant macroH2A1.1 Enhances Nonhomologous End Joining-dependent DNA Double-strand-break Repair and Reprogramming Efficiency of Human iPSCs.9
350727992022Analysis of histone variant constraint and tissue expression suggests five potential novel human disease genes: H2AFY2, H2AFZ, H2AFY, H2AFV, H1F0.3
354723082022High expression of H2A histone family member Y promotes the proliferation and autophagy of hepatocellular carcinoma cells.0
355118672022Histone Variant macroH2A1.1 Enhances Nonhomologous End Joining-dependent DNA Double-strand-break Repair and Reprogramming Efficiency of Human iPSCs.9
340032522021Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions.15
341127842021The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation.17
342239062021LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2.12
348875602021Evolution of a histone variant involved in compartmental regulation of NAD metabolism.2
348996872021Exploring the Prognostic Value, Immune Implication and Biological Function of H2AFY Gene in Hepatocellular Carcinoma.3
340032522021Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions.15
341127842021The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation.17

Citation

Dessen P

MACROH2A1 (macroH2A.1 histone)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58143