ALOXE3 (arachidonate lipoxygenase 3)

2019-08-01  

Identity

HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
ARCI3,E-LOX,eLOX-3,eLOX3

Other Information

Locus ID:

NCBI: 59344
MIM: 607206
HGNC: 13743
Ensembl: ENSG00000179148

Variants:

dbSNP: 59344
ClinVar: 59344
TCGA: ENSG00000179148
COSMIC: ALOXE3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000179148ENST00000318227Q9BYJ1
ENSG00000179148ENST00000380149J3KPH2
ENSG00000179148ENST00000448843Q9BYJ1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
334354992021Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients.11
335813112021The ALOXE3 gene variants from patients with Dravet syndrome decrease gene expression and enzyme activity.0
334354992021Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients.11
335813112021The ALOXE3 gene variants from patients with Dravet syndrome decrease gene expression and enzyme activity.0
318831582020Variants in NIPAL4 and ALOXE3 cause autosomal recessive congenital ichthyosis in Pakistani families.1
326180012020Phenotypic suppression of acral peeling skin syndrome in a patient with autosomal recessive congenital ichthyosis.0
318831582020Variants in NIPAL4 and ALOXE3 cause autosomal recessive congenital ichthyosis in Pakistani families.1
326180012020Phenotypic suppression of acral peeling skin syndrome in a patient with autosomal recessive congenital ichthyosis.0
299350032019Identification and association of recurrent ALOXE3 mutation with non-bullous congenital ichthyosiform erythroderma in two ethnically distinct Pakistani families.0
306787112019The associations of DNA methylation alterations in oxidative stress-related genes with cancer incidence and mortality outcomes: a population-based cohort study.12
299350032019Identification and association of recurrent ALOXE3 mutation with non-bullous congenital ichthyosiform erythroderma in two ethnically distinct Pakistani families.0
306787112019The associations of DNA methylation alterations in oxidative stress-related genes with cancer incidence and mortality outcomes: a population-based cohort study.12
278681472017Congenital Ichthyosis and Recurrent Eczema Associated with a Novel ALOXE3 Mutation.0
278681472017Congenital Ichthyosis and Recurrent Eczema Associated with a Novel ALOXE3 Mutation.0
265782032016Novel mutations in the genes TGM1 and ALOXE3 underlying autosomal recessive congenital ichthyosis.6

Citation

Dessen P

ALOXE3 (arachidonate lipoxygenase 3)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58154/js/lib/favicon/css/template-nav.css