ALOXE3 (arachidonate lipoxygenase 3)

2019-08-01 Affiliation

Identity

HGNC

ALOXE3

LOCATION

17p13.1

LOCUSID

59344

ALIAS

ARCI3,E-LOX,eLOX-3,eLOX3

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 59344
MIM: 607206
HGNC: 13743
Ensembl: ENSG00000179148

Variants:

dbSNP: 59344
ClinVar: 59344
TCGA: ENSG00000179148
COSMIC: ALOXE3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000179148	ENST00000318227	Q9BYJ1
ENSG00000179148	ENST00000380149	J3KPH2
ENSG00000179148	ENST00000448843	Q9BYJ1

Expression (GTEx)

100

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
33435499	2021	Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients.	11
33581311	2021	The ALOXE3 gene variants from patients with Dravet syndrome decrease gene expression and enzyme activity.	0
33435499	2021	Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients.	11
33581311	2021	The ALOXE3 gene variants from patients with Dravet syndrome decrease gene expression and enzyme activity.	0
31883158	2020	Variants in NIPAL4 and ALOXE3 cause autosomal recessive congenital ichthyosis in Pakistani families.	1
32618001	2020	Phenotypic suppression of acral peeling skin syndrome in a patient with autosomal recessive congenital ichthyosis.	0
31883158	2020	Variants in NIPAL4 and ALOXE3 cause autosomal recessive congenital ichthyosis in Pakistani families.	1
32618001	2020	Phenotypic suppression of acral peeling skin syndrome in a patient with autosomal recessive congenital ichthyosis.	0
29935003	2019	Identification and association of recurrent ALOXE3 mutation with non-bullous congenital ichthyosiform erythroderma in two ethnically distinct Pakistani families.	0
30678711	2019	The associations of DNA methylation alterations in oxidative stress-related genes with cancer incidence and mortality outcomes: a population-based cohort study.	12
29935003	2019	Identification and association of recurrent ALOXE3 mutation with non-bullous congenital ichthyosiform erythroderma in two ethnically distinct Pakistani families.	0
30678711	2019	The associations of DNA methylation alterations in oxidative stress-related genes with cancer incidence and mortality outcomes: a population-based cohort study.	12
27868147	2017	Congenital Ichthyosis and Recurrent Eczema Associated with a Novel ALOXE3 Mutation.	0
27868147	2017	Congenital Ichthyosis and Recurrent Eczema Associated with a Novel ALOXE3 Mutation.	0
26578203	2016	Novel mutations in the genes TGM1 and ALOXE3 underlying autosomal recessive congenital ichthyosis.	6

Citation

Dessen P

ALOXE3 (arachidonate lipoxygenase 3)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58154/js/lib/teaching-explorer/css/template-card.css