CLEC12B (C-type lectin domain family 12 member B)

2021-06-01  

Identity

HGNC
CLEC12B
LOCATION
12p13.2
LOCUSID
387837
ALIAS
UNQ5782

Other Information

Locus ID:

NCBI: 387837
MIM: 617573
HGNC: 31966
Ensembl: ENSG00000256660

Variants:

dbSNP: 387837
ClinVar: 387837
TCGA: ENSG00000256660
COSMIC: CLEC12B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000256660ENST00000338896Q2HXU8
ENSG00000256660ENST00000338896A0A140VK10
ENSG00000256660ENST00000396502Q2HXU8
ENSG00000256660ENST00000539155F5H4H7
ENSG00000256660ENST00000544853Q2HXU8

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
343109512022CLEC12B Decreases Melanoma Proliferation by Repressing Signal Transducer and Activator of Transcription 3.1
348961192022CLEC12B Is a Melanocytic Gene Regulating the Color of the Skin.2
343109512022CLEC12B Decreases Melanoma Proliferation by Repressing Signal Transducer and Activator of Transcription 3.1
348961192022CLEC12B Is a Melanocytic Gene Regulating the Color of the Skin.2
340201402021Selective expression of a C-type lectin receptor, Clec12b, on skin mast cells.0
347807822021CLEC12B suppresses lung cancer progression by inducing SHP-1 expression and inactivating the PI3K/AKT signaling pathway.3
340201402021Selective expression of a C-type lectin receptor, Clec12b, on skin mast cells.0
347807822021CLEC12B suppresses lung cancer progression by inducing SHP-1 expression and inactivating the PI3K/AKT signaling pathway.3
303509152019Pinpointing a potential role for CLEC12B in cancer predisposition through familial exome sequencing.1
303509152019Pinpointing a potential role for CLEC12B in cancer predisposition through familial exome sequencing.1
175627062007Identification of CLEC12B, an inhibitory receptor on myeloid cells.17
175627062007Identification of CLEC12B, an inhibitory receptor on myeloid cells.17

Citation

Dessen P

CLEC12B (C-type lectin domain family 12 member B)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58246/case-report-explorer/favicon/meetings/