SOX13 (SRY-box transcription factor 13)

2021-06-01  

Identity

HGNC
SOX13
LOCATION
1q32.1
LOCUSID
9580
ALIAS
ICA12,Sox-13

Other Information

Locus ID:

NCBI: 9580
MIM: 604748
HGNC: 11192
Ensembl: ENSG00000143842

Variants:

dbSNP: 9580
ClinVar: 9580
TCGA: ENSG00000143842
COSMIC: SOX13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143842ENST00000367204Q9UN79
ENSG00000143842ENST00000480326H0YDQ5
ENSG00000143842ENST00000525442E9PKD6
ENSG00000143842ENST00000528591E9PPW0
ENSG00000143842ENST00000618875Q9UN79

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by WntREACTOMER-HSA-195721
TCF dependent signaling in response to WNTREACTOMER-HSA-201681
Deactivation of the beta-catenin transactivating complexREACTOMER-HSA-3769402

References

Pubmed IDYearTitleCitations
382706212024THAP9-AS1 promotes nasopharyngeal carcinoma progression through targeted regulation of the miR-185-5p/SOX13 axis.0
382706212024THAP9-AS1 promotes nasopharyngeal carcinoma progression through targeted regulation of the miR-185-5p/SOX13 axis.0
371496932023Sox13 and M2-like leukemia-associated macrophages contribute to endogenous IL-34 caused accelerated progression of acute myeloid leukemia.0
371496932023Sox13 and M2-like leukemia-associated macrophages contribute to endogenous IL-34 caused accelerated progression of acute myeloid leukemia.0
356118282022Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/β-catenin signaling pathway.2
356118282022Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/β-catenin signaling pathway.2
331097792021SOX13 gene downregulation in peripheral blood mononuclear cells of patients with Klinefelter syndrome.1
331097792021SOX13 gene downregulation in peripheral blood mononuclear cells of patients with Klinefelter syndrome.1
321119842020SOX13 promotes colorectal cancer metastasis by transactivating SNAI2 and c-MET.25
324615892020Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.14
321119842020SOX13 promotes colorectal cancer metastasis by transactivating SNAI2 and c-MET.25
324615892020Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.14
313539582019SOX13 dependent PAX8 expression promotes the proliferation of gastric carcinoma cells.18
313539582019SOX13 dependent PAX8 expression promotes the proliferation of gastric carcinoma cells.18
200289822010Interaction between Hhex and SOX13 modulates Wnt/TCF activity.18

Citation

Dessen P

SOX13 (SRY-box transcription factor 13)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58251