CAMSAP3 (calmodulin regulated spectrin associated protein family member 3)

2021-06-01  

Identity

HGNC
CAMSAP3
LOCATION
19p13.2
LOCUSID
57662
ALIAS
KIAA1543,NEZHA,PPP1R80

Other Information

Locus ID:

NCBI: 57662
MIM: 612685
HGNC: 29307
Ensembl: ENSG00000076826

Variants:

dbSNP: 57662
ClinVar: 57662
TCGA: ENSG00000076826
COSMIC: CAMSAP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000076826ENST00000160298Q9P1Y5
ENSG00000076826ENST00000446248Q9P1Y5

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381908682024CAMSAP3, a microtubule orientation regulator, plays a vital role in manifesting differentiation-dependent characteristics in keratinocytes.1
381908682024CAMSAP3, a microtubule orientation regulator, plays a vital role in manifesting differentiation-dependent characteristics in keratinocytes.1
370193002023CAMSAP3 negatively regulates lung cancer cell invasion and angiogenesis through nucleolin/HIF-1α mRNA complex stabilization.1
370193002023CAMSAP3 negatively regulates lung cancer cell invasion and angiogenesis through nucleolin/HIF-1α mRNA complex stabilization.1
335666842021Rab14/MACF2 complex regulates endosomal targeting during cytokinesis.3
335666842021Rab14/MACF2 complex regulates endosomal targeting during cytokinesis.3
302826322018Loss of CAMSAP3 promotes EMT via the modification of microtubule-Akt machinery.16
302826322018Loss of CAMSAP3 promotes EMT via the modification of microtubule-Akt machinery.16
280893912017CAMSAP3-dependent microtubule dynamics regulates Golgi assembly in epithelial cells.4
280893912017CAMSAP3-dependent microtubule dynamics regulates Golgi assembly in epithelial cells.4
267157422016CAMSAP3 orients the apical-to-basal polarity of microtubule arrays in epithelial cells.60
273491802016Cadherin 23-C Regulates Microtubule Networks by Modifying CAMSAP3's Function.8
276935092016The CAMSAP3-ACF7 Complex Couples Noncentrosomal Microtubules with Actin Filaments to Coordinate Their Dynamics.23
278021682016Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7.43
267157422016CAMSAP3 orients the apical-to-basal polarity of microtubule arrays in epithelial cells.60

Citation

Dessen P

CAMSAP3 (calmodulin regulated spectrin associated protein family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58306/case-report-explorer/gene-fusions-explorer/tumors-explorer/