LAYN (layilin)

2021-06-01  

Identity

HGNC
LAYN
LOCATION
11q23.1
LOCUSID
143903
ALIAS
-

Other Information

Locus ID:

NCBI: 143903
MIM: 618843
HGNC: 29471
Ensembl: ENSG00000204381

Variants:

dbSNP: 143903
ClinVar: 143903
TCGA: ENSG00000204381
COSMIC: LAYN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204381ENST00000375614Q6UX15
ENSG00000204381ENST00000375615Q6UX15
ENSG00000204381ENST00000436913Q6UX15
ENSG00000204381ENST00000525126E9PQU7
ENSG00000204381ENST00000525866E9PR90
ENSG00000204381ENST00000528924A0A0D9SFG0
ENSG00000204381ENST00000530962E9PK64
ENSG00000204381ENST00000533265E9PMI0
ENSG00000204381ENST00000533999E9PQY8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
373353372023Comprehensive landscape of the miRNA-regulated prognostic marker LAYN with immune infiltration and stemness in pan-cancer.0
376424732023Elevated Layilin-Positive Monocyte Levels in the Peripheral Blood of Patients with Systemic Lupus Erythematosus Reflect Their Autoimmune Status.0
373353372023Comprehensive landscape of the miRNA-regulated prognostic marker LAYN with immune infiltration and stemness in pan-cancer.0
376424732023Elevated Layilin-Positive Monocyte Levels in the Peripheral Blood of Patients with Systemic Lupus Erythematosus Reflect Their Autoimmune Status.0
363980672022ncRNA-Regulated LAYN Serves as a Prognostic Biomarker and Correlates with Immune Cell Infiltration in Hepatocellular Carcinoma: A Bioinformatics Analysis.2
363980672022ncRNA-Regulated LAYN Serves as a Prognostic Biomarker and Correlates with Immune Cell Infiltration in Hepatocellular Carcinoma: A Bioinformatics Analysis.2
336761822021Layilin promotes mitochondrial fission by cyclin-dependent kinase 1 and dynamin-related protein 1 activation in HEK293T cells.2
336761822021Layilin promotes mitochondrial fission by cyclin-dependent kinase 1 and dynamin-related protein 1 activation in HEK293T cells.2
325390732020Layilin augments integrin activation to promote antitumor immunity.17
325390732020Layilin augments integrin activation to promote antitumor immunity.17
307611222019LAYN Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Gastric and Colon Cancers.189
307611222019LAYN Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Gastric and Colon Cancers.189
264105312015Roles of layilin in TNF-α-induced epithelial-mesenchymal transformation of renal tubular epithelial cells.12
264105312015Roles of layilin in TNF-α-induced epithelial-mesenchymal transformation of renal tubular epithelial cells.12
251501532014Secretion of inflammatory factors from chondrocytes by layilin signaling.5

Citation

Dessen P

LAYN (layilin)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58377